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Illustrating what I have maintained for years, new
research has shown that people with high levels of Lipoprotein(a) or Lp(a),
have a much higher risk of heart disease.
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Analyzing the findings from 27 studies, British
researchers found that those patients with high levels of Lp(a) had
a 70% higher risk of developing heart disease over a period of 10
years.
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Lp(a) is a substance that consists of an LDL "bad
cholesterol" part plus a protein (apoprotein a), whose exact
function is currently unknown.
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Despite previous conflicting results concerning
the importance of Lp(a), researchers maintain that this study shows
that Lp(a) has a "clear association" with heart disease
risk.
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Researchers also maintain that a person's Lp(a)
is largely governed by genetics. For example, people of African decent
tend to have higher levels than Caucasians.
Currently, there are no available drugs to lower Lp(a),
although researchers state that some research suggests estrogen therapy
may help.
Circulation September
5, 2000:102.
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