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January 14 2001
Low Cholesterol Causes Aggressive Behavior and Depression

 

Despite the fact that most people are worried about having cholesterol levels that are too high, yet another study has found that low cholesterol is actually associated with adverse behavioral effects such as aggression and depression.

While the medical establishment continues to push the suppression of cholesterol levels to abnormally low levels, it is not widely known that there is a significant amount of evidence linking low cholesterol to aggressive behavior and depression.

According to researchers from Yale University School of Medicine, "The well-documented negative association between serum cholesterol and aggressive behavior has led Kaplan (Psychosom Med 1994 Nov-Dec;56:479-84) to propose a cholesterol-serotonin hypothesis of aggression.

According to this hypothesis, low dietary cholesterol intake leads to depressed central serotonergic activity, which itself has been reported in numerous studies of violent individuals."

  • Researchers studied 25 violent psychiatric patients

  • For 7 days, the patients wore signaling devices that emitted an average of seven signals a day.

  • Following each signal, patients filled out a mood questionnaire.

The authors found that "Total serum cholesterol (TSC) concentration was positively associated with measures of affect, cognitive efficiency, activation, and sociability, suggesting a link between low TSC and dysphoria."

"These findings are consistent with the cholesterol-serotonin hypothesis and with the substantive literature linking both aggression and depression to depressed central serotonergic activity," they conclude.

Journal of Behavioral Medicine, December 1, 2000; 23: 519-529



Dr. MercolaDr. Mercola's Comments:

Well, with so many people taking drugs to lower their cholesterol and half the population predicted to take statin drugs in the future, it is time that we seriously re-evaluated what we are doing with them. Just like our weight, there is an optimum with cholesterol as well. Some people believe that the lower your cholesterol, the healthier you are.

Nothing could be further from the truth. If your cholesterol is too low you will have an increased risk of mood disorders, depression, stroke, and violence. And these are only the KNOWN effects right now. There are likely many more currently unknown and unstudied

This best predictor of heart disease with respect to cholesterol is the HDL/total cholesterol ratio.

Related Articles:

Cholesterol Drugs May Increase Cancer Risk

Low Cholesterol Linked to Depression

Lowering Cholesterol Could Cause Violent Behavior

Low Cholesterol Linked to Stroke Risk

Low Cholesterol and Albumin Bad Signs in Elderly

Statins May Impair Brain Function

Half of Population Will be Taking Statins

Low Cholesterol May Affect Mood

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Robert K.
[ Joined on 02/08 ] [ Posted on February 19, 2008 ]
       
   
 
Novice User

Dr. Mercola...I am 66 years old.  I have 6 stents in my heart. I am on 40 mg of Zocar daily.  My cholesterol is 167, HDL 52, LDL 67, Triiglycerides 85.  

I am told that because of the stents it is important to remain on the statin.  

I take 3000 mg of niacin, 4000 mg fish oil, 2000 mg of cod liver oil, 2000 mg of lecithin, 200 mg coq10 every day.  I workout on the treadmill or out walking 40 minutes a day.  I workout on my total gym and free weights.  I don't eat red meat, eat fruit, veggies and lots of walnuts and almonds and lots of fish.

My number one question is with the 6 stents, how safe would it be to stop the statin.  I am told by all my cardiologist to reamin on the statins.

Any help from you on this?

Bob

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