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A compound that makes peppers hot effectively
lowers blood sugar in dogs, say researchers from Jamaica,
suggesting that it might
someday be used to treat diabetes in humans.
Peppers are used by traditional Jamaican
healers to treat diabetes, but the compound, capsaicin, has
never been formally tested. The compound is also used in the
US to treat painful nerve damage called diabetic neuropathy.
The investigators tested the effects
of capsaicin on blood sugar and insulin levels in dogs.
Beginning 2 hours after receiving a sugary
treat, blood sugar levels in the dogs that received capsaicin
were well below those in dogs that did not receive the pepper
protein, the authors report.
The levels of insulin -- the hormone
that controls the body's handling of sugar -- were higher
after 2.5 hours in the dogs that received capsaicin, the report
indicates, even though the insulin appeared to stick less
strongly to blood cells.
The researchers note that they are not
sure whether the pepper extract increases the release of insulin
or slows down its breakdown.
Phytotherapy
Research August 2001;15:391-394
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