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Patients with type 2 diabetes who incorporate
stress management techniques into their routine care can significantly
reduce their average blood glucose levels.
Stress can increase glucose levels in people
with diabetes, making them more susceptible to long-term physical
complications such as eye, kidney or nerve disorders.
This is the first large study to show that a
simple, cost-effective treatment can have a meaningful therapeutic
effect on the control of blood sugar, said the researchers. Such
stress management techniques include instructions on how to identify
everyday life stressors and how to respond to them with such techniques
as progressive muscle relaxation and breathing exercises.
Patients in the stress management group showed,
on average, a 0.5 percent reduction on the hemoglobin A1c (HbA1c)
test - a standard laboratory test used to determine average blood
glucose levels in people with diabetes.
However, 32 percent of the patients in that
group showed an even greater improvement by lowering their glucose
level by 1 percent or more.
That amount of glucose level reduction is what
the Food and Drug Administration (FDA) considers sufficient when
reviewing drugs seeking approval for diabetes control.
The patients were randomly enrolled in the educational
sessions either with or without stress management training. Stress-management
techniques were taught by nurses or graduate students specifically
trained for the study.
The training included progressive muscle relaxation,
mental imagery, breathing techniques and instructions on how to
modify one's physiologic, cognitive and behavioral responses to
stress.
At the beginning of the study, and at subsequent
times throughout the year-long tracking period, patients were tested
using the HbA1c test to evaluate their blood sugar control and with
various questionnaires to assess their trait anxiety. Such trait
anxiety included perceived levels of stress, anxiety and psychological
health. All participants were at least 30 years old and currently
managing their diabetes with diet, exercise and/or non-insulin medications.
Experiencing stress is associated with the release
of hormones that lead to energy mobilization - known as the 'fight
or flight' response. Key to this energy mobilization is the transport
of glucose into the bloodstream, resulting in elevated glucose levels,
which is a health threat for people with diabetes.
Stress also can disrupt diabetes control indirectly
through its effects on diet and exercise.
After six months, the control group began to
show deterioration in their glucose levels, while the stress management
group continued to improve.
By the end of one year, 32 percent of the patients
randomized to stress management had HbA1c levels that were lower
by 1 percent or more. In contrast, only 12 percent of the control
subjects had levels that were this much lower. The effect cannot
be explained by changes in body mass index, diet or exercise because
the two groups did not differ on these variables during the year
they were followed.
The HbA1c test has been shown to be effective
in predicting coronary disease and other risks to people with diabetes,
including the development of microvascular complications in the
kidneys or eyes.
Diabetes Care January
2002
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