A recent study that investigated the effects of taking low-dose aspirin daily for close to four years, found that only participants with compromised kidney function (defined as a serum creatinine level greater than 1.3) benefited significantly.
The patients with compromised kidney function who took 75 mg of aspirin daily had decreased risk of cardiovascular events and myocardial infarction as compared with those who took a placebo. The risk of bleeding from the aspirin was similar in all study participants. Previous studies have shown that low-dose aspirin reduced cardiovascular events by 15 percent and myocardial infarction by 36 percent, however major bleedings increased by 65 percent.
Journal Hypertension November 2002 20(11):2301-2307