http://articles.mercola.com/sites/articles/archive/2002/06/05/estrogen-gallstone.aspxHormone replacement therapy (HRT) may raise a woman's likelihood of developing gallstones. A gallstone can develop when bile, cholesterol, calcium salts and other substances come together to form a mass in the gallbladder, the tiny sac tucked under theenCommunityServer 2008.5 SP1 (Build: 31106.3070)