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A fourth report in the US of a patient with a Staph
bacteria infection resistant to the antibiotic vancomycin has prompted
officials from the Centers for Disease Control and Prevention (CDC) to
emphasize their guidelines on preventing the spread of these bacteria.
The CDC also reported January 6 that laboratories around
the US might not be correctly testing for these antibiotic-resistant strains
of bacteria, which is crucial in preventing their spread.
One bacteria of concern, Staphylococcus aureus,
is a common cause of infection in hospitalized patients. In recent years,
experts have become very concerned about the increased incidence of strains
of the bacteria that fail to succumb to all but a few antibiotics. This
is known as antibiotic resistance, and most experts think that it is due
to worldwide overuse of antibiotics. As the theory goes, if all the bacteria
causing an infection are not eradicated with an antibiotic, then the remaining
bacteria become stronger and more resistant to future use of the same
antibiotic.
Eventually, this can lead to strains of bacteria
that show resistance to antibiotics held in reserve for such cases, such
as vancomycin. This raises the specter of infections for which no
antibiotic treatment may be available, putting patients' lives
at great risk. The CDC reports a case in April 1999, of a 63-year-old
woman in an Illinois hospital with a Staph infection. The woman had kidney
failure and had already received the antibiotic vancomycin, which should
kill most strains of Staphylococcus aureus.
However, after being on vancomycin for 25 days,
the physicians found three strains of Staphylococcus resistant to several
different antibiotics, including vancomycin. Despite treatment with vancomycin
and two other antibiotics, the women died. The hospital screened family
members, healthcare workers at the hospital, and other patients at the
hospital and found no evidence that the antibiotic-resistant bacteria
strains had spread to any of them. The CDC officials note that in response
to reports of infections with antibiotic-resistant strains of bacteria
it is conducting a nationwide search for other cases like the one described
here.
Morbidity and
Mortality Weekly Report 2000;48:1165-1171.
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