Cow's milk-based formulas used for infants with cow's milk allergy are based on hydrolyzed proteins, with the formulas that are designed to prevent allergic responses being extensively hydrolyzed (e.g., Nutramigen), which means that the protein is broken down into its component amino acids. However, reactions to such formulas are occasionally reported.
In this study, researchers found some unexpected protein material in this type of formula.
Upon further investigation, they determined that these were corn proteins.
Researchers speculate that the protein originated from the corn starch in Nutramigen.
The researchers state that they are unsure of the clinical importance of this finding, but that it is possible that the corn protein may be responsible for some of the allergic reactions to this type of formula.
Pediatric Allergy and Immunology July, 2000; 11: 106-110
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