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August 20 2000
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CoQ10 for Respiratory Problems

 

This report from France illustrates the importance and value of coenzyme Q10 (ubiquinone), especially concerning respiratory function.

  • The authors note that the respiratory-chain deficiencies are a broad group of largely untreatable diseases.

  • There is a subclass of patients with these disorders who suffer from a coenzyme Q10 deficiency.

  • Deficiency of coenzyme Q10-dependent respiratory-chain activities was identified in muscle biopsy, circulating lymphocytes, and cultured skin fibroblasts of 2 siblings with this disorder.

  • Undetectable coenzyme Q10 in cultured fibroblasts supported the diagnosis of widespread coenzyme Q10 deficiency.

  • The patients were treated with oral CoQ10 (5 mg/kg daily), which resulted in a substantial improvement of their condition over 3 years of therapy.

The authors conclude that particular attention should be paid to the fact that some patients with respiratory-chain enzyme deficiency may be successfully treated by oral CoQ10.

Lancet August 18, 2000; 356: 391-95



Dr. Mercola Dr. Mercola's Comments:
CoQ10 is a helpful nutrient for a variety of conditions. It is particularly useful for congestive heart failure and breast cancer where doses would be 100 mg 3-4 times per day.

Related Article:

FDA Grants Orphan Drug Status to CoQ10

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