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400
IU of vitamin D inadequate in many women
Postmenopausal women should
take supplements of both vitamins D and K, in order to insure good bone
health, according to a new study from the Netherlands.
Researchers analyzed the nutritional
status of these 2 vitamins in postmenopausal women with both normal and
low bone mineral density (BMD).
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The women were divided
into four groups. One group received 350-400 IU vitamin D3, 80 micrograms
Vitamin K1, both of these vitamins, or a placebo.
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At the start of the study,
researchers found that the vitamin K status of the women was positively
correlated with their BMD.
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Supplementation
with vitamin K was able to bring up to normal, the vitamin K status
of the women with low BMD.
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Although supplementation
with 350-400 IU of vitamin D did improve their vitamin D status, it
was not an adequate enough doses to prevent a significant (29%) decline
during the winter months in women with low BMD.
Vitamin D status was assessed
in the women by measuring the serum levels of 25-hydroxyvitamin D [25(OH)D]
and to assess the vitamin K status, the serum carboxylated osteocalcin
(%carbOC) was used.
Therefore,
as a result of their findings, the researchers note that Dutch postmenopausal
women need to be supplemented with more than 400 IU of vitamin D, along
with 80 micrograms of vitamin K, to maintain optimal bone health.
European
Journal of Clinical Nutrition August 2000; 54, 626-631.
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