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Common
bacteria can help cut
the risk that hospitalized infants will develop
diarrhea by 80%.
The research team investigated whether
providing the infants with formula containing Lactobacillus
GG (LGG) bacteria could prevent onset of diarrhea. LGG is
known as a "good" microbe, or "probiotic,"
which is naturally present in the gut and can help balance
the presence of other harmful microbes, warding off intestinal
problems.
Hospitalized infants are at an especially
high risk of acquiring intestinal microbes such as the rotavirus,
which can cause diarrhea and possibly lead to infant death.
In the study, half the children were given a formula containing
LGG twice daily, while the others received an inactive placebo
formula.
One third of the children receiving the
placebo formula developed diarrhea, compared with only 7%
of the children receiving the formula containing LGG.
This translates
to an 80% reduction in the risk
of developing diarrhea.
Four children would need to be treated
with the "good" bacteria to prevent a single case
of diarrhea. There were no
adverse side effects reported from the treatment.
There are several theories how probiotics
might help prevent intestinal disorders: they may compete
with harmful microbes for nutrients in the body, or may actually
synthesize microbe-fighting compounds.
The Journal
of Pediatrics 2001;138:361-365
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