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Conflicts of interest
that arise from industry-funded medical research are widespread
and can affect the outcomes of the research, according to
a new study.
The study found
that scientific studies funded by an industry-related source
are close to four times more likely to yield results that
favor the industry than those sponsored by independent sources.
Researchers analyzed
data from eight individual articles that had addressed the
association between industry sponsorship and research outcome.
They combined data from these studies, which together amounted
to 1,140 original studies, in order to reach a conclusion
that may be more reliable than the original studies alone.
Results showed
that industry-sponsored studies were 3.6 times more likely
to have results that favored the industry than studies with
no financial ties to the industry.
While researchers
noted that industry sponsorship of medical research has contributed
to scientific progress, conflicts of interest presented by
financial ties to the industry may undermine the integrity
of the research.
They stressed that
in order to preserve the benefits and future advancement of
scientific research, measures will need to be taken to understand
and monitor the consequences of industry-backed research.
As a first step, they recommend that investigators and sponsors
fully disclose the nature of their relationship and results
from clinical trials be made available in a publicly accessible
database.
Journal
of the American Medical Association January 22, 2003;289:454-465
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