All those great numbers and facts might lead you to believe sucralose is a pretty safe product, but nothing could be further from the truth. Animal research has shown that sucralose can cause many problems such as:

• Reduced growth rate in newborns and adults at levels above 500 mg/kg.day

• Decreased red blood cells - - sign of anemia (at levels abofe 1500 mg/kd/day

• Decreased thyroxine levels (thyroid function) (According to McNeil, since this only occurred on male rats and no abnormalities were observed with the thyroid tissue, this was considered insignificant.)

• Mineral losses (magnesium and phosphorus) McNeil stated that these patterns were variable and at times not dose related so they were not significant.

• Decreased urination

• Enlarged colon (The FDA Final Rule states cecal enlargement is often seen with poorly absorbed substances and is not significant.)

• Enlarged liver and brain (McNeil stated these were insignificant due to a lack of a dose response.)

• Shrunken ovaries

• Shrunken thymus aboe 3 grams per day

• Enlarged and calcified kidneys (McNeil stated this is often seen with poorly absorbed substances and was of no toxicological significance. The FDA Final Rule agreed that these are findings that are common in aged female rats and are not significant.)

• Increased adrenal cortical hemorrhagic degeneration (McNeil stated that this is a variable finding common in aged rats and not toxicologically significant.)

• Increased cataracts (McNeil stated that cataracts were discovered upon microscopic sections of the eye tissue and that this was not as accurate as in-life ophthalmological examinations and did not reveal any treatment- related ocular findings.

• Abnormal liver cells (The FDA Final Rule states that this was only marginal and probably not treatment related due to the severity of the lesion was not contaminant with the dosage.)

McNeil concluded that all of these findings could be explained by reasons other than sucralose toxicity and were insignificant. This seems to be a pattern in all of McNeil's study conclusions. I find it suspect that for every single adverse finding in the animal studies, McNeil always has some rationale that renders it "insignificant." Their downplaying every harmful finding makes it seem as if they are more interested in making sucralose appear safe than making sure that the people are not harmed.

The FDA concluded that most of these findings had no toxicological significance and those that did such as the decrease in thymus weight and the decreased red blood cells, would not be a problem because they occurred at doses of sucralose much higher than what people would consume.. As a physician, I beg to differ. I believe that these findings are not of no significance." Many of these are symptoms of serious pathology.

If you think using Splenda is worth risking your health, than go ahead and use it. Just keep this in mind: Nearly every month we receive a report from someone who has had an adverse effect from Splenda. The fact is, many people are uneducated about the reverse effect this product can have on your health and body and find out only after they experience a negative reaction.

If dramatically reducing your intake of sweet, whether it is sugar or alternative sweeteners like Splenda, feels close to "impossible" for you, I strongly urge you to read my bestselling TOTAL HEALTH Program (which has a special offer now!) It presents my entire dietary program that has helped many tens of thousands of patients, and one of the key reasons this book has received such widespread critical acclaim is its strong focus on eliminating unhealthy dietary cravings and addictions like "sweet addiction" through natural solutions like nutritional typing and much more.

For further information on Splenda you can review my Splenda toxicity page and read through the many testimonials people have sent in about this product.

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