Past studies have shown that one of the contributing factors to
heart attacks and strokes is low-density lipoprotein. (LDL cholesterol)
Now, researchers have found another type of cholesterol that may
be just as, if not more, dangerous: Chylomicrons.
Chylomicrons, a class of lipoproteins, are defined as metabolized
balls of fat and cholesterol. They enter the blood stream through
the intestines after a meal and accumulate on arterial walls. Doctors
find it difficult to measure chylomicrons due to how quickly they
process. For example, when a patient gives a blood sample after
fasting for 12 or more hours, chylomicron cholesterol will usually
include only three percent of all the cholesterols present in the
sample. The bulk of the sample (70 percent) will be comprised of
LDL.
It is for this reason that most researchers are led to believe
that LDL is the leading cause of the development of coronary artery
disease. However, these findings have prompted a question of contradictory
proportions: Why is it that 40 percent of people prone to suffering
from a stroke or heart attack have low or normal LDL levels?
Some researchers believe understanding
chylomicrons and their metabolism may answer this question and the
role it plays in the development of:
- Diabetes
- Obesity
- Other cardiovascular diseases
EurekAlert
November 23, 2004
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