While synthetic hormone replacement therapy (HRT) has previously
been believed to protect against heart disease and stroke, studies
have offered evidence of a reversal. Researchers found that synthetic
HRT is actually linked to an increased risk of stroke, typically
ischemic in type (caused by blockages of blood flow to the brain)
and severe in nature.
In fact, synthetic HRT boosts the risk of stroke by almost one-third
and the risk of fatal or disabling stroke by more than half. These
conclusions were drawn based on 28 trials involving nearly 40,000
women, showing that in women receiving HRT:
- Strokes increased by 29 percent
- Fatal or disabling strokes increased by 56 percent
One of the trials reviewed also linked synthetic HRT with higher
risks of breast cancer and heart attack. The trial, which included
almost 17,000 women over 50, indicated those taking HRT for five
years doubled the risk of life-threatening blood clots.
British
Medical Journal January 7, 2005 (Free Full Text Artilce)
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