Taking oral contraceptives may be more dangerous than many women
realize. According to research on mice, the synthetic hormones found
in oral contraceptives were discovered to create deformities in
the prostate glands, which have been linked to prostate cancer and
bladder disease later on.
Why are these findings important?
As many as 3 percent of women taking oral contraceptives become
pregnant without knowing it and continue exposing their baby to
the drug many months into pregnancy. And since a woman taking oral
contraceptives typically misses an average of three pills a month,
her risk of pregnancy increases. With 60 million women taking oral
contraceptives in Europe and America, that means as many as 2 million
women could become pregnant and still be taking the pills.
Mice Testing
Researchers tested the effect of a typical oral contraceptive on
the development of an embryo by giving pregnant mice the contraceptive
ethinylestradiol; the dosage was scaled down to one-fifth of the
normal human dose and was administered for five days.
A group of mice were also exposed to low levels of a similar estrogenic
chemical known as bisphenol A, an environmental pollutant found
in plastics and the lining of food cans.
The results ...
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Due to chemical exposure, there was a consequent increase in
the number and size of prostate ducts and a narrowing of the
bladder neck in male mouse fetuses.
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This effect, which could lead to difficulties with urination
as well as prostate cancer, is a direct forecast of how these
drugs affect the human reproductive system, according to researchers.
Proceedings
of the National Academy of Sciences May 10, 2005;102(19): 7014-7019
(Free Full-Text Article)
New
Scientist May 3, 2005
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