Use Accutane for Acne and Risk Bowel Disease
August 29, 2006
A study has at last confirmed the long-held theory that the acne drug isotretinoin (accutane) can cause an increased risk of inflammatory bowel disease (IBD). IBD includes Crohn's disease and a similar condition called ulcerative colitis.
Possible, Probable, or Highly Probable
A review of all reports of accutane-associated IBD showed that between 1997 and 2002, there were 85 cases of accutane-caused IBD. Accutane was graded as a "highly probable" cause in four cases, a "probable" cause in 58 cases, and a "possible" cause in 23. In no case was the accutane considered a "doubtful" cause.
Not Recommended for Some
Doctors are advising that those with a prior personal history or family history of IBD should avoid accutane.