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Vitamin K Linked to Better Vascular Health, Fewer Varicose Veins

Varicosis, also known as varicose veins, may be attributable to a lack of vitamin K, according to a new study in the “Journal of Vascular Research.”

Inadequate levels of vitamin K may reduce the activity of the matrix GLA protein (MGP), which in turn has been identified as a key player in the development of varicosis. Since vitamin K is required to activate MGP, it is believed that adequate dietary intake of vitamin K is a prerequisite for the prevention of varicose veins.

There are two main forms of vitamin K:

1. K1 (phylloquinone, aka phytonadione)
2. K2 (menaquinones)

Vitamin K3 is a synthetic variant of the vitamin, which is not recommended for human consumption.

Vitamin K1 is found in green leafy vegetables, including lettuce, broccoli, and spinach, and makes up about 90 percent of the vitamin K in the Western-style diet.

Vitamins K2 include several menaquinones (MK-n, with the n determined by the number of prenyl side chains), such as MK-4 found in meats; MK-7, MK-8, and MK-9 found in fermented food products like cheese and natto.

Journal of Vascular Research July 20, 2007; 44(6):444-459 (Free Full Text PDF Report)

Food Production Daily August 23, 2007

 



Dr. Mercola''s Comments Dr. Mercola's Comments:

Varicose veins – those unsightly, painful bulges that appear on the legs when blood pools in the veins – are a reality for between five to 30 percent of the adult population, with women being three times more likely to develop varicosis than men.

How do You Prevent Varicose Veins?

Risk factors for developing varicose veins include:

  • Age
  • Obesity and/or multiple pregnancies
  • Lack of physical activity
  • Standing occupations
  • Genetic predispositions, and connective tissue abnormalities 

The name of the game here is mainly prevention. For example, you may not realize that constantly crossing your legs will contribute to varicose veins. Other major, but easily reversible factors, are lack of walking-type exercises, and constipation.  

Your diet is one fundamental source of preventive “medicine.”

Fermented foods, such as natto, typically have the highest concentration of vitamin K found in the human diet, and can provide several milligrams of vitamin K2 daily. This level far exceeds the amount found in dark green vegetables. For example, vitamin K2 concentration after the consumption of natto has been shown to be about 10 times higher than that of vitamin K1 after eating spinach. Unfortunately, most Americans do not eat many fermented foods.

Vitamin K2 is synthesized by intestinal bacteria, and is absorbed from the distal small bowel. Keep in mind that taking antibiotics hampers vitamin K2 absorption.

Vitamin K1 is typically found in dark green leafy vegetables. The following table lists some vegetable sources of vitamin K that you should consider adding to your diet:

Food

Vitamin K*

Collard Greens

440

Spinach

380

Salad Greens

315

Kale

270

Broccoli

180

Brussels Sprouts

177

Food

Vitamin K*

Cabbage

145

Olive Oil

55

Asparagus

60

Okra

40

Green Beans

33

Lentils

22

Vitamin K – The Forgotten Vitamin

Vitamin K is a fat-soluble vitamin most well-known for the important role it plays in blood clotting. However, vitamin K is also absolutely essential to build strong bones, as it serves as the biological "glue" that helps plug the calcium into the bone matrix. Some studies have actually shown vitamin K to be equivalent to Fosamax-type osteoporosis drugs.

Vitamin K is vital in heart disease prevention as well, because it helps prevent hardening of the arteries – a common risk factor in coronary artery disease and heart failure.

Other beneficial effects of vitamin K include:

  • Helpful against Alzheimer’s disease.
  • Topical vitamin K may help to reduce bruising.
  • Vitamin K deficiency may interfere with insulin release and blood sugar regulation in ways similar to diabetes.
  • May have antioxidant properties.
  • Beneficial in the treatment of cancer, including lung- and liver cancer.

Vitamin K is a fat-soluble vitamin. This is important to note, because it means that dietary fat is necessary for the absorption of this vitamin. One easy way to do this is by adding the liquid vitamin K drops I recommend, directly into your fish oil or krill oil. This will ensure that the vitamin K is well-absorbed by your body. Alternatively, you could add it to any other food that contains healthy fat.

Do You Need a Vitamin K Supplement?

The plant-based vitamin K1 (phylloquinone), and the bacterially produced vitamin K2 (menaquinone) are so important that, although I don’t typically recommend adding extra supplements to your diet, vitamin K is one of the few supplements you may want to consider, especially if you have (or your family has) a history of osteoporosis or heart disease.

The following conditions may put you at an increased risk of vitamin K deficiency:

  • Eating a poor or restricted diet.
  • Chron’s disease, ulcerative colitis, celiac disease, and other conditions that interfere with nutrient absorption.
  • Liver disease that interferes with vitamin K storage.
  • Taking drugs such as broad-spectrum antibiotics, cholesterol drugs, and aspirin.

I recommend 3,000 mcg of vitamin K per day. If you are pregnant or nursing, avoid vitamin K supplemental intakes higher than the RDA (65 mcg) unless specifically recommended and monitored by your physician.

If you’ve experienced stroke, cardiac arrest, or are prone to blood clotting, don’t take vitamin K without consulting your physician first.



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Comment on This Article Community Comments (36)
 
 
Posted On Aug 24, 2007
Vitamin K is HORRIBLY underrated. We have kept all of the fat soluble vitamins in the dark waaayyyy too long. Weston Price's book " Nutrition and Physical Degeneration" told us of the importance of the fat solubles A, D, E, K years ago.  Just like other nutrients look at how many different kinds of vitamin K exist. Just like vitamin D, K is also a prohormone. It is used to make osteocalcin which attracts and keeps calcium in the bone and out of the soft tissue. Vitamin K is found mostly in liver, dark greens, and raw fermented foods, and they are made by the bacteria in our gut. Americans use to eat liver from clean pasture fed animals, dark greens, and fermented foods regularly. Now we avoid liver (too much of that evil cholesterol), iceberg lettuce is our green of choice (worthless), rarely eat anything fermented (thanks refrigerators and food processors), and take lots of antibiotics (bacteria must die). Yeah, it's poor genetics and too much cholesterol that make us sick and diseased. What is sad is that we are just now starting to look at vitamin K's importance and none of us will fully understand its importance in our lifetime.

 
phooey
Savvy User Savvy User, Joined On 2/2007
phooey  
 
 
 
Posted On Aug 24, 2007
Just as an FYI, those who may have a hyper-coagulation issue with their blood should not just start upping their vitamin K intake as this can cause more problems with their blood thinning medications.  I cannot remember the exact article where I read this; but, I know it is somewhere here on the Mercola site.  Probably under hemochromatosis or clotting disorders????  At any rate, I do remember reading about it and informing my mother as she is on blood thinners.  The doctors have never been able to determine what her actual blood clotting disorder is (she's had it since she was 7 when she had a blood clot to her liver). 


 
A.M.E.
Savvy User Savvy User, Joined On 6/2006
A.M.E.  
Replied

Russ Bianchi
Savvy User Savvy User Joined On 9/2006
Russ Bianchi  
 
Posted On Aug 24, 2007
Coumadin (Warfarin), an anticoagulant,  or blood thinner, some times found in statin drugs, is a typical warning the MD's worry about, in combination with Vitamin K, because of the SYNTHETIC form of Vitamin K in many supplements, OTC's, and prescription protocols, that are not readily solubilized, and can lead to internal bleeding, hemorrhaging, and DEATH.

Coumadin should NEVER be consumed by pregnant women and besides the heightened chance of miscarriage, can lead to other birth defects in the fetus.

Naturally solubilized Vitamin K, in proper sequencing with naturally occurring amino acids, not found in synthetic forms of Vitamin K, and that is naturally occurring in some botanically based plants, can be utilized safely, in some, but not all circumstances.


A.M.E.
Savvy User Savvy User Joined On 6/2006
A.M.E.  
 
Posted On Aug 24, 2007
Thank you Russ, that explains it a bit more.  I know my mother has been on Coumadin since age 7 and also has to give herself shots of Heparin (I don't know how often but it's like her EpiPen).  I have recently been able to convince her to try to see a naturopathic doctor to try to get her off of some of the many mediations she's been on for so long.  When she came to take care of me after my surgery she had a gallon freezer bag full of just her daily medications and some pain meds.  It's scary the amount of drugs doctors will put people on.  I think she is finally realizing that there is a better way.


Patty D
Savvy User Savvy User Joined On 6/2007
Patty D  
 
Posted On Aug 27, 2007
I HAVE to tell ya'll what happened this past week.  I have been on Coumadin for over 9 years because I had blood clots in my lungs and they found a genetic clotting disorder.  Vitamin K antagonizes Coumadin....they don't tell you NOT to eat things with Vitamin K, but to keep your diet consistent.  The end of April, shortly after I started my natural health journey, my INR (test for therapeutic activity of Coumadin) dropped to almost normal and has stayed low.   The week before last the doctor bumped my dose sky high to get me in the therapeutic range.  After a few days, I noticed I had sores breaking out on my arms, my feet hurt so bad I basically couldn't walk, it seemed like every bone and every muscle in my body was hurting and I was terribly nauseated.  I was confused, because I had been experiencing all those problems when I started eating natural foods, and they had resolved or become tolerable.  Then it dawned on me the only change was the huge Coumadin dose.   I got online and started researching and found out that every single thing I was experiencing could be linked to coumadin. I did not take it Wednesday night and called my doc Thursday.  I told her I was not going to take it anymore and would manage my clotting disorder with supplements.  She was pretty upset, warning me I could die etc.  I told her I'm an RN, I totally understand the risks,  but that I also believe in this diet and have faith God will protect me.  I have been non therapeutic since April, and haven't had any problems with clots (I've been taking fish oil and Vit E...which you aren't supposed to take with Coumadin either) and I've now added garlic and ginko.   I'm starting to feel a lot better and the sores are healing too.


Phantom O Banjo
Savvy User Savvy User Joined On 9/2006
Phantom O Banjo  
 
Posted On Aug 27, 2007
Patty good thing Doc's have a license or they be dangerous.  You should have said since when have doctors cured death?


Sheila C
Apprentice User Apprentice User Joined On 1/2007
Sheila C  
 
Posted On Sep 13, 2007

Please know that they started using Warfarin (coumadin) as rat poison in 1956.  But have since quit using it because the predators were dying also.



evw
Apprentice User Apprentice User Joined On 6/2007
evw  
 
Posted On Sep 13, 2007

I have to applaud you Patty, I WISH I could get my friend a doctor off of her medication that suppresses her immune system. I told her if she cannot let her immune system get better with supplements and NO pharmacuetical she will never get better. BIG PHARMA wants to keep you sick and on their drugs. I also am amazed that you are part of the system but have realized what it is all about!

High Five!



GregB777
Apprentice User Apprentice User Joined On 5/2007
GregB777  
 
Posted On Sep 13, 2007

To Patty:

Your symptoms are not unheard of for Coumadin users. It is a dangerous drug with terrible long term side effects. Here is why: Coumadin blocks vitamin K from being recycled. This is helpful to stop clotting, because clotting enzymes are vitamin K dependent. Unfortunately, vitamin K also is essential in MANY other processes NOT involving clotting.The two most important are the gamma carboxylation of matrix-GLA proteins and osteocalcin, and the production of sphingolipids in the brain, the most familiar which is myelin.Myelin is the insulation on nerve cells-it is what is destroyed in Multiple Sclerosis!Rats on warfarin(AKA COUMADIN)can no longer make myelin in their brains! That is because myelin needs vitamin K to be produced!Search MEDLINE for warfarin and myelin.Taking coumadin is likely causing the insulation on your nerves to wear away,the result of which would be MS like symptoms of burning, dizziness and other troubles.They have also discovered that vitamin K2 given to rats with MS-like disease HEALS THEM!Again search MEDLINE for Multiple Sclerosis and vitamin K.Coumadin also stops gamma carboxylation of matrix-GLA proteins and osteocalcin.These are the proteins that carry calcium around the body and put it in the proper place.They are like calcium "taxis".Vitamin K allows these proteins to deposit the calcium in the correct place in the body--in your bones and teeth.Without vitamin K,the proteins don't work right,and they deposit Ca places it DOESN'T belong-like your arteries and veins(hardening of the arteries,varicoses)joints(osteoarthritis)muscles, kidneys(stones).Ever wonder why older people LOSE calcium from their bones,but have it deposit where it DOESN'T BELONG?Does that make any sense to you?If you are supposedly calcium deficient,why is your body depositing it in your arteries then?No, part of the problem is that you don't have enough vitamin K2 (ditto with Mg.) Anyway, coumadin causes a lot of troubles,as you have found out.Check MEDLINE.



jkroot
Novice User Novice User Joined On 8/2006
jkroot  
 
Posted On Sep 14, 2007

Patty D...kudos for you!!!! Your Dr is not the last word. They want you to believe that, but they are NOT!!!!  It is about the money. When you find a physician that has you in their office and prescribes a remedy (allopathic or naturopathic) that FIXES the problem and only requires one or two follow-up visits to confirm you are healing....THAT IS A PHYSICIAN!!!  WHEN THEY WANT YOU IN THEIR OFFICE MONTH AFTER MONTH AND THEY ARE ONLY MANAGING YOUR PROBLEM, YOU ARE IN THE MONEY MILL!!! Threats such as "You may die!" are a last ditch effort and a full blown admission that "I don't really know what is wrong with you, but you need to keep seeing me so I can eventually try to figure it out, if at all!"


 
 
 
Posted On Aug 24, 2007
I noticed that this study was done exclusively in men,  Women have the highest incidence of varicose veins why wasn't the study done on women.

Mary

 
mmc88121
Moderator User Moderator User, Joined On 11/2006
mmc88121  
Replied

Magnolia
Savvy User Savvy User Joined On 6/2006
Magnolia  
 
Posted On Sep 15, 2007

Looking at the list of researchers on the study, it seemed to me that men outnumbered women. Could that be a possible reason the study covered men? ;)


 
 
 
Posted On Sep 13, 2007
I am a 79 year old female and back in 91 I was diagnosed with atrial fib. and put on heart medication as well as coumadin. After 2 years on coumadin I started getting side effects. My mouth was sore, like when you burn your tongue with a hot liquid and I lost all taste. I could smell, especially pizza and when I ate it , everything tasted like cardboard. Told my Dr. and he tried to change every prescription except coumadin. Nothing changed. I finally researched and found the product "nattokinase" and ordered it. I told my Dr. I was going off coumadin and taking the nattokinase. He told me I would have a severe stroke or die. My response was that was OK because living with the side effects was not worth living. Having to go to him each year for a checkup and to get my prescription refilled, he was astonished to see what good health I was in. The second year, he stated "look at you" I asked what he meant? He stated "my father was a doctor and if you were my fathers patient he would tell you to go home and continue doing what I was doing!" (protecting himself from a possible future lawsuit???) Year 4 he called me and asked me to send him the literature I had on nattokinase. He had a male patient who was having the same ill effects I had and refused to take coumadin any more. He was going to recommend the nattokinase. This amazed me that a heart doctor would acknowledge that there is something better than rat poison.

 
LorraineZuk
Novice User Novice User, Joined On 11/2006
LorraineZuk  
 
 
 
Posted On Aug 27, 2007
Vitamin E is also good for varicose veins.

 
Sheila C
Apprentice User Apprentice User, Joined On 1/2007
Sheila C  
 
 
 
 
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