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October 13 2007
Do YOU Understand the Dangers of Hormone Therapy?

Despite widespread publicity, the 2002 landmark study on the potential dangers of hormone therapy for postmenopausal women is completely unknown to most women. 

New research from the Stanford University School of Medicine discovered that only 29 percent of the women surveyed knew anything about the study two years later. Additionally, only 40 percent of the women were able to identify possible risks and benefits linked to hormone therapy. 

Hormone therapy is used to ease your symptoms of menopause, but has also been widely prescribed for preventive purposes, based in part on earlier observational studies that had suggested it could help protect women against heart disease, weak bones, and dementia. 

In July 2002, the Women’s Health Initiative (WHI) abruptly ended its combination of estrogen and progestin therapy study, as their data discovered higher rates of breast cancer, heart attacks, strokes, and blood clots in the population taking the hormones, compared to those taking placebos. 

Later, in April 2004, WHI also halted the portion of the study for estrogen-only therapy, after finding the hormone did not offer any protective heart disease prevention, but rather increased your risk of stroke and blood clots. 

The WHI findings triggered enormous changes in the use of hormone therapy, and prescriptions had dropped 38 percent by 2003. 

Senior author Randall Stafford, MD, PhD, said their latest survey indicates there’s a huge problem in communicating crucial health information to patients effectively, which in turn is indicative of an even larger problem – ensuring that people can make informed decisions about their medical care. 

Menopause April 10, 2007

Women’s Health Initiative June 21, 2007

WHI March 2, 2007 (The Estrogen-Alone Study Links)

Women’s Health Initiative (The Estrogen-Plus-Progestin Study Links)

Eurekalert September 18, 2007



Dr. MercolaDr. Mercola's Comments:

I have been posting information about the dangers of synthetic hormone replacement therapy (HRT) two years before the WHI studies were even completed – or halted, I should say -- due to the devastating health complications for the women who participated in the studies.  It was crystal clear to me back then that this was a disaster. 

However, I didn’t always believe this and in the mid-80’s I was actually a paid speaker for the company that makes Premarin. I used to lecture to physicians about its benefits in preventing diseases like osteoporosis, and used their industry funded studies to support my delusional belief. 

Fortunately, I was (and still am) a truth seeker and I finally understood how I was being deceived by the drug companies. That is one of the reasons I am on this mission, as I am a reformed brainwashed physician who has seen the light of truth. 

One of the primary purposes of this site is to provide you with the information you need to make informed decisions about your health BEFORE you end up a victim of conventional drugs. 

A Fake Disease Gets a Phony Cure

Meanwhile, the powers that be -- namely, the multi-national drug companies -- kept prescribing these useless, dangerous drugs for the "disease" of menopause, which is in fact a completely natural condition that happens to most women.

Menopausal symptoms are not signs of illness, and they can be effectively relieved without toxic chemicals.

Unfortunately, doctors usually have you take an HRT regimen that includes the completely unnatural progestin. Synthetic progestins (like Provera), are responsible for many of your side effects of HRT, which include:

  • Osteoporosis
  • Blood clots
  • High blood pressure
  • Vaginal bleeding
  • Rash and acne
  • Weight gain

While HRT was previously believed to protect you against heart disease and stroke, and therefore prescribed as a form of “prevention,” several studies have since proven the opposite.

One such study, published in the British Medical Journal in January 2005, found that synthetic HRT is actually linked to an increased risk of stroke, typically ischemic (caused by blockages of blood flow to your brain), and severe.

In fact, synthetic HRT boosts your risk of stroke by almost one-third, and your risk of fatal or disabling stroke by more than half.

One of the trials reviewed in that meta analysis also linked synthetic HRT with higher risks of both breast cancer and heart attack. The trial (which included almost 17,000 women over 50), also found taking HRT for five years doubled your risk of life-threatening blood clots.

If estrogen supplementation is in fact indicated, and necessary, such as after you’ve had your ovaries surgically removed (surgical menopause), many experts believe your optimal bioidentical hormone estradiol is all you would really need.

I also believe that menopausal hot flashes that do not resolve with phytoestrogens such as black cohosh, are another valid indication for short-term estrogen use. However, if estrogen is used, it is nearly always wise to use it in conjunction with natural progesterone.

Bioidentical Hormones

Estradiol is bioidentical to the primary human female hormone, as opposed to Premarin (the most popular estrogen replacement), which comes from horse estrogens.

You should avoid using animal estrogens for hormone replacement, as there are excellent human bioidentical estrogen hormones easily available through any compounding pharmacist. The one that seems to work the best for most women is a transdermal preparation of human estrogen.

Application through your skin allows lower doses than oral, and decreases production of potentially dangerous estrogen metabolites.

Unfortunately, there is still much unnecessary concern about bioidentical estradiol supplementation. What the FDA, most doctors, and patients do not realize is that bioidentical hormone supplements can actually optimize your health.

Ideally, your hormone levels should be monitored by either blood, urine, or saliva, to ensure they reach a target level that corresponds to the reference ranges for healthy young women.

Conquering Menopause With Simple Lifestyle Changes

Simple lifestyle changes can offer you your natural means to optimize your hormone levels as well:


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Community Comments ( 54 )
Comment on this Article
  
  
Patty D
[ Joined on 06/07 ] [ Posted on September 20, 2007 ]
15 Points        
   
 
Savvy User
"This study suggests that we have a flawed mechanism for getting information down to the level of the population,"
Another factor is the bombardment of the population by pharmaceutical ads on TV and in every written media.  On TV, side effects are at the end of the ad, where people's attention has already wandered, in written media, the side-effects, precautions etc are microscopic.  Doctors don't WANT to have a frank discussion about the meds and when a patient tries to have one, their concerns are pooh-poohed as over-reaction.  Docs and other prescribers are more than happy to "assume" patients will read the dumbed down patient information pamphlets that they get when the prescription is filled.
 [ Reply ]
Mercola
  
Russ Bianchi
[ Joined on 09/06 ]  [ Posted on September 20, 2007]
7 Points        
   
Savvy User
  Mercola
"Pamphlets"...for the MD'sto get away from liability from the lawyer tribe...one wonders if the tort lawyers, the insurance cabal, and reactive drug pushers are all really working with each other, in a rope-a-dope of the American public's collective wallet?
Mercola
  
DizzyIzzy1
[ Joined on 06/07 ]  [ Posted on September 21, 2007]
11 Points        
   
Savvy User
  Mercola
Yeap, it's so true. When I was on the pill - the first one I was on, anyway - I of course read the side effects pamphlet so I could know what to be aware of, I wasn't happy about being on it but thought I'd try, purely for the contraceptive reasons. When half the list happened to me - including severe depression, crying at EVERYTHING, enormously itchy rashes, mood swings, numbness up my back...

I went back to the Dr to switch to another. He simply said that I'd been reading too much of the caution list in the packet, to ignore it, give it another few months and it would go away. It took me bursting into tears, yelling at him and refusing to leave until he gave me something else for him to change the prescription... I'm off it altogether now, but even so, the second one he gave me was - despite having side effects of its own - a million times better and all those symptoms were gone within 2 weeks.
  
  
Kim H
[ Joined on 06/06 ] [ Posted on September 21, 2007 ]
13 Points        
   
 
Apprentice User
From Dr. Mercola website   http://www.mercola.com/2005/jan/26/hrt_strokes.htm

"When it comes to estrogen, many experts believe all most women need is estradiol , which is bioidentical to the primary human female hormone. Unfortunately there is still much unnecessary concern about bioidentical estradiol supplementation. What the FDA and most doctors and patients do not realize is that bioidentical hormone supplements can actually optimize your health. Ideally, these levels should be monitored by either urine or blood levels so they reach a target level that correspond to the reference ranges for healthy young women".

It is important to understand that there is a huge difference between the synthetic HRT used in this study and bio-identical hormones. Bio-identical hormones cannot be patented and are usually only available via a  Dr.'s prescription from a compounding pharmacy, which is the reason (in my opinion) that doctors still prescribe the junk that was used in this study.  The only way companies have been able to patent bio-identical hormones is via a delivery system, ie. the patch.

Ladies, if you are suffering the from peri/post-menopausal symptoms  and cannot control them via diet and/or lifestyle change, go see a gynecologist who will work with you.  Get a full panel of blood tests as suggested by Dr. Mercola to check you hormone levels and to make sure you don't have other underlying problems that are causing your symptoms.  You may have to go through several Dr.'s until you find one who will work with you, I know I did. Read up on the subject, so you are educated when you see your doc.  There are some great books out there on the subject.  My favorites are by Dr. E. L Vliet. 
 [ Reply ]
Mercola
  
Kim H
[ Joined on 06/06 ]  [ Posted on September 21, 2007]
12 Points        
   
Apprentice User
  Mercola
Part 2:
Women should get their hormones levels checked, via a blood test, when they are young and their ovaries are still functioning at normal levels. A normal level for one woman, may not be normal for another.  If you know your levels when you are young, then you will be better equipped to make decisions when they drop.  If you don't know your prior "normal" levels, then it becomes a matter of trial and error, which can be frustrating. After trying to cope on my own, and going through a series of Dr.'s who just wanted to hand me a pill, I finally found an excellent GYN who was also an endocrinologist.  When he got the results of my blood tests he was shocked.  All of my other findings were excellent (high HDL, low triglycerides, every thing else in normal range) but my hormones were almost flatlined!  Almost no estrogren or testosterone.  He actually was shocked that my symptoms weren't worse than they were. I had my uterus (but not my ovaries) removed when I was 33.  I didn't suffer any known side effects at the time and didn't need supplementation.  I don't know if that had anything to do with my extreme case or not. We worked together thru trial and error and came up with a prescription for estradiol that worked for me. He explained to me how to tell if I was getting too much or too little. He said my body would tell me, and he was correct.  I have had to go to other Dr.'s since because I have relocated and it has been a fight to even get new blood tests to compare with my previous levels.  If you don't feel you need Bio-identical supplementation - great, but don't let the studies on fake HRT keep you from seeking help if you need it!!!!
Mercola
  
Kim H
[ Joined on 06/06 ]  [ Posted on September 21, 2007]
15 Points        
   
Apprentice User
  Mercola
Not sure how "estradiol" got linked in my response. I guess because I quoted Dr. M's site. I will add that currently bio-identical testosterone can only be administered (to my knowledge) via a prescription cream from a compounding pharmacy.  Testosterone for women got a bad rap because Dr.'s were prescribing amounts WAY too high for a woman. A woman's body NEEDS a small amount, but only a small amount.  Once again, work with a doctor who will listen to you and work with you.
vociferum :  What was as bad as the docs who blindly told their patients to remain on the fake hormones, were those docs that panicked and took the easy way out and just told their patients to quit the hormones that they were taking cold turkey!  Friends of mine who did this thought they were going to loose their minds.
A year of so after getting my hormones regulated, I relocated and had to start going to an HMO. I ask for an appt. with a GYN to get retested and get my prescription renewed. I ask for a GYN who specialized in menopausal issues, but instead I got a nurse-practitioner who was also a midwife, whose specialty was OB!  She refused my request for a blood-test and dropped the dosage on my HRT, even though it had been working perfectly (after a year of trial and error to get it right).  I took the new lowered prescription (as I didn't have a choice) and within 2-3 weeks some of my symptoms came back.  I called the help desk and fortunately got a nurse who understood my dilemma and changed my dosage back to the original amount.  A short time later, when visiting a GP for an entirely unrelated issue, I was asked what prescriptions I was taking. I told him the only prescription meds I took was bio-identical HRT, and without having ever seen him before, and with NO tests or records, he said "Well, we're going to get you off of those!!!" I am now paying out of pocket for my GYN!!
Mercola
  
AnnInMaine
[ Joined on 12/06 ]  [ Posted on October 13, 2007]
1 Points        
   
Novice User
  Mercola

I recently went to the New England Womans Center in Portland Maine.

Im 48 and was suffering from numerous symptoms including menopause. Susan Doughty the owner,prescribed for me a Hormone Saliva test. From the results I learned that have adrenal exhaustion that effects all the other hormones in my body.This is, from what I have learned, the most accurate way to be tested for hormone levels.  Im currently using Licorice root extract from Avena Botanicals and DHEA from the Womans Pharmacy and having wonderful results! For the menopause Im taking low dose Kariva. BTW her mentor

and close friend is Christine Northrup!

Mercola
  
4healthytruth
[ Joined on 10/07 ]  [ Posted on October 14, 2007]
       
   
Novice User
  Mercola

Kim there are bio-identical forms of testosterone on the market from a prescription.

Mercola
  
Damon1
[ Joined on 10/07 ]  [ Posted on October 15, 2007]
       
   
Novice User
  Mercola

This is a question for everyone posting in this blog.  The lead article speaks of estradiol, yet I've read much that those that tend to get cancer are high in estradiol.  Woman that remain cancer-free tend to be high on estriol, not estradiol.  I don't recall the 3rd mentioned hormone, but women with healthy levels are 70/15/15 - 70 estriol, 15 estradiol & the other 15 the other hormone.  Probably would know that if I was female.

Anyway - my wife wears a Vivelle-Dot patch and her doc swears it the "safest" available, yet it is majority estradiol.

Dr. Mercola - can you comment?

Mercola
  
Conie
[ Joined on 06/06 ]  [ Posted on October 18, 2007]
1 Points        
   
Novice User
  Mercola

You are so right! The sad thing is that, for us over age 65, doctors are "so sorry, but I'm afraid we are not taking medicare patients right now." Even though we have another good insurance from where we retired, since medicare sets the amount the doctor can receive, doctors do not make as much money off medicare patients as they do of the general population. I don't really blame them for not taking medicare patients. But the system is flawed. No matter how high a salary we made before we retired, we have no choice but to use medicare. Our salary was not enough to pay doctors outright. Oh, and we still pay huge amounts to keep our "secondary" insurance.

So, if you are under 65, I advise you to make a project of doctor hopping until you find a good one.    

  
  
samurai
[ Joined on 04/07 ] [ Posted on September 20, 2007 ]
12 Points        
   
 
Savvy User
Not just hormone replacement therapy in PMW, but adding any and all hormones in all ages!
Also, the foods we eat, and how much it effects our hormones.  I have been estrogen dominate in the past, and one of our good buddies told me on the website that soy induces bad estrogen production.  He sure was right.  I checked all sorts of labels, and sure enough, soybean oil is in LOTS of stuff.  Also, soy letchin??  What the heck is that???
Sorry to be on my soap-box here, but as someone who has paid the price, and learned my lesson, xenogens are bad, bad, bad.  Don't mess with your hormones people!! 
Oh, and just say "no" to Depo-Provera. 
 [ Reply ]
Mercola
  
Mercola Fan
[ Joined on 11/06 ]  [ Posted on September 21, 2007]
10 Points        
   
Apprentice User
  Mercola
I have a friend who is getting into a pyramid direct marketing group that will be selling a SOY based diet (Medifast..made by an RX co.). I told my friend it is not wise to encourage folks to live on a diet that relies completely on soy protein. He was surprised, so I offered all of Dr Mercola's info on soy, as well as other info. He forwarded the info to his rep. and expressed concern.  The rep proceeded to attack Dr Mercola and his credibility. He told my friend to look at the wikipedia reference to Dr Mercola to learn more. My friend concluded my sources (mainly Dr Mercola)  were questionable, that soy was THE best form of protein, and signed up with the group selling RX garbage.

So I decided to see what the wikipedia definition said.
 It does not begin to define Dr Mercola's stature in the internet community and maligns him by implying he is a profit driven conman. There is an invitation above his name telling folks they need more reference material to offer the most unbiased definition:

This article or section needs sources or references that appear in reliable, third-party publications. Alone, primary sources and sources affiliated with the subject of this article are not sufficient for an accurate encyclopedia article. Please include more appropriate citations from reliable sources .

Purhaps some of us can assist them
Mercola
  
PepperR23
[ Joined on 06/06 ]  [ Posted on September 21, 2007]
10 Points