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October 13 2007
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Green Tea -- Beats Avandia for Diabetes, and No Deadly Side Effects

A compound in green tea, EGCG (epigallocatechin gallate), works as well in moderately diabetic mice as GlaxoSmithKline’s diabetes drug Avandia, according to researchers from Sweden’s Karolinska Institute.

In the study, 5-week-old moderately diabetic and severely diabetic mice were fed EGCG or given Avandia. After five and 10 weeks of treatment, the blood sugar and insulin levels of the mice were tested.

Moderately diabetic mice did just as well on the green tea extract as they did on Avandia. Severely diabetic mice did not benefit as much from EGCG.

Researchers said the EGCG, though less potent than Avandia, “exerted changes that were similarly beneficial.”

Upon examining the mice’s pancreases at the end of the study, the researchers found that EGCG preserved insulin-producing tissue and limited damage that could worsen diabetes.

The results suggest that green tea extract supplements may also help treat diabetes in humans.

Worldwide, more than 240 million people have diabetes, and the number may reach 380 million within two decades, according to the International Diabetes Federation.

European Association for the Study of Diabetes meeting in Amsterdam, Netherlands September 19, 2007

The China Post September 21, 2007



Dr. MercolaDr. Mercola's Comments:
It is certainly noteworthy that Epigallocatechin gallate (EGCG), the most powerful catechin found in tea, appears to help diabetes just as much as the disasterous drug Avandia.

Avandia helps sensitize your body to insulin; when it first came on the market, it was considered a breakthrough medication for blood-sugar control. More than six million people have taken the drug in the eight years it has been available.

However, it’s since come out that Avandia causes a 43 percent higher risk of heart attack, and possibly death.

These are hefty risks for a drug designed to treat a disease that is virtually 100 percent curable with SIMPLE lifestyle changes (more on these later).

What is EGCG, and Where Can I Find It?

You’ve probably heard EGCG mentioned in the media, as it’s been getting a lot of positive press recently, but you may not know exactly what it is.

EGCG is a catechin found in green tea. Catechins belong to the polyphenol family (polyphenols in green tea may constitute up to 30 percent of the dry leaf weight), and they’re widely acclaimed for disease prevention and anti-aging purposes. For centuries, catechins have been known to:
  • Neutralize the effects to your body of harmful fats and oils
  • Inhibit bacteria and viruses such as HIV, hepatitis, and herpes
  • Improve digestion
  • Protect against oxidation in your brain and liver
  • Help promote healthy gums
EGCG in particular is a very noteworthy antioxidant; it’s estimated to be 25-100 times more potent than vitamins C and E, and can fight a host of illnesses beyond diabetes, such as:
A recent study even found that EGCG may help to neutralize some of the toxins formed by high-fructose corn syrup (HFCS), and help to reduce the association between high-fructose corn syrup and diabetes (though the best solution here is obviously to avoid HFCS in the first place).

EGCG is found in high quantities in green tea, and this is a beverage that you can certainly enjoy in moderation.

I say “in moderation” because I still believe that pure water is what you were designed to drink primarily, and once you veer too far from this fluid you can run into severe health problems.

Next to water, though, I believe drinking green tea from 100-percent quality tea leaves is one of the most nutritious beverages you can consume.

When choosing a green tea, be aware that previous research has found high levels of fluoride present in some teas. Fluoride is a toxic substance that can have profoundly negative effects on your body. So if you consume large amounts of green tea for health benefits, you might want to invest some time in researching a brand that is quite low in fluoride.

Have Diabetes? Try THIS Before Avandia

As I said earlier, Avandia has been fraught with dangerous side effects since at least the year 2000, when it was found to play a role in liver failure.

If you have diabetes, medication is not the answer you’re looking for. Knowing which foods to eat, and what exercises to perform, is. Doctors usually talk about diabetes as a disease of blood sugar. However, type 2 diabetes is also a disease of insulin and leptin signaling -- both of which can be corrected through your diet.

So before resorting to drugs for diabetes, I would suggest learning about how food and exercise can be your allies to better health.

My book, Take Control of Your Health, will arm you with everything you need to know to start eating right for your body and taking care of yourself physically and emotionally. I’ve also compiled a comprehensive, free online guide that will educate you on how to make type 2 diabetes finally disappear.

Related Articles:

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Community Comments ( 19 )
Comment on this Article
  
  
Bridestein
[ Joined on 12/06 ] [ Posted on September 21, 2007 ]
17 Points        
   
 
Savvy User
-"A chemical found in green tea helped moderately diabetic mice tolerate sugar"-
Unfortunately people will use this information as a way to have their cake and eat it too.
 [ Reply ]
Mercola
  
Reesacat
[ Joined on 01/07 ]  [ Posted on September 21, 2007]
16 Points        
   
Savvy User
  Mercola
(Sigh)  Probably put the green tea extract in their Gallon O'Diet Soda
and have the supersize meal with the fried apple pies..........................
Mercola
  
DizzyIzzy1
[ Joined on 06/07 ]  [ Posted on September 24, 2007]
3 Points        
   
Savvy User
  Mercola
Oh Reesacat, thank you, you just solved my 'what do I have for dinner?' ponderings for the day.... ;)



Funny how people try to make themselves feel so much better about the crap they eat by justifying it with findings like this. Is it really that hard to just buy some veges and cook them yourself?
Mercola
  
Bridestein
[ Joined on 12/06 ]  [ Posted on September 24, 2007]
3 Points        
   
Savvy User
  Mercola
Energy - thank you. I was feeling very overwhelmed that day by the pettiness and acted too impulsively.
I really appreciate having access to such a wealth of information and enjoy reading all the responses. I've rarely learned so much so quickly and you guys are a thought-provoking bunch, for sure! ^_^
Mercola
  
Nathan
[ Joined on 04/07 ]  [ Posted on September 26, 2007]
3 Points        
   
Savvy User
  Mercola
What a joke, a whole lot of diabetic mice sitting around drinking green tea so they can tolerate sugar. Those in charge of our health research need  to get a life. Confusion reigns. They may as well say an elephant ate cheese and his wrinkles smoothed out, so cheese is good for our skin.

When the circus is in trouble they send in the clowns, that's for sure.

If you want some straight talk about health, visit this helpful website. www.friendswithcancer.com   They don't insult your intelligence.

Mercola
  
Pat Ormsby
[ Joined on 06/06 ]  [ Posted on October 15, 2007]
1 Points        
   
Savvy User
  Mercola

You said it right, Bridestein!  In Japan, we drink green tea until it's coming out our ears, but we have an epidemic of diabetes to match America's.  From my observations, it has a lot to do with sugar addiction and the myth that only carbs are good for you, but pesticides and various kinds of pollution are probably also to blame.

Mercola
  
Chorizo
[ Joined on 10/07 ]  [ Posted on October 17, 2007]
       
   
Novice User
  Mercola

I feel like some of the comments speculating on what people might "do" with the information were very obnoxious and pretentious. I'm an insulin-dependent diabetic and have been that way since I was a child.  My diet would rival Dr. Mercola's.  I've tried his guide on 'how to make diabetes disappear," and unforutunately it hasn't worked for me.    Therefore, I'm personally intrigued by the green tea news.  I'm specifically referring to the comment regarding diabetics 'having their cake and eating it too' and 'excuses to eat fried apples."  While we all know that idiots like that exist, there are many people like me who could use the information to improve on theri long=time diabetic struggle.  Not all forms of diabetes respond to diet control.  

Whether the study actually means anything is a whole other story, especially considering the fact (that another reader pointed out) that the diabetic epidemic in Japanese population is rising despite Japan's high green tea consumption. Perhpas a study should be conducted amongst green tea drinking folks and diabetics so that we can find out a real solid answer.  Of course, like another commenter also pointed out, no pharmaceutical company would ever fund that study since it would only lead to the demise of their profit on insulin if the study did in fact yield promising results.  

  
  
mmc88121
[ Joined on 11/06 ] [ Posted on September 22, 2007 ]
11 Points        
   
 
Moderator User
So they looked at green tea as a treatment for diabetes 70 years ago according to the article, why did they not use the, the pharmaceutical companies could not make money off of it.

Mary
 [ Reply ]
Mercola
  
Aaltrude
[ Joined on 04/07 ]  [ Posted on September 24, 2007]
4 Points        
   
Savvy User
  Mercola
Spot on Mary. The same goes for all natural remedies. I am also convinced that the reason why gluten intolerance (where there is no coeliac disease present) is not acknwledged by the medical profession, is because there is no drug to treat it. I understand one company is trying to develop a drug that will allow these people to eat gluten foods without any side effects. If they are successful, I bet we will suddenly find that doctors are being encouraged to find the one in three (as estimated by Dr Fine's research) that are gluten intolerant.
  
  
Russ Bianchi
[ Joined on 09/06 ] [ Posted on September 21, 2007 ]
11 Points        
   
 
Savvy User
Look no further than the glorified soda pop out from a Coke/Nestle joint venture, branded ENVIGA, "with ECGC", at nonefficacious parts per million dosages, to sell essentially small amounts of flavor, coloring, sweetened (with toxic sucralose or aspartame, depending on the market) and filtered tap WATER, to find exploitation of this "finding" already.

Hmmmm, trace element amounts of EGCG, mixed with fake colorings/flavors and toxic high intensity sweeteners...???

"Sounds healthy to me, yeah, if we can convince the public with Vitamin Water (non at all metabolized because the trace element amounts are synthetic of the alleged vitamins or minerals and a recent Coke acquisition for over $4 Billion Dollars, per The Wall Street Journal) why not EGCG?!"

This quote comes from a soulless Coke distributor marketing ("Evil Genus") person.
 [ Reply ]
  
  
seg
[ Joined on 11/06 ] [ Posted on September 24, 2007 ]
10 Points        
   
 
Savvy User
AVANDIA simply will not go away eh !!! In time they would wish they had pulled this garbage of the market. I can see the headlines GSK sued again !!!

While green tea is definately one of nature's power houses we have to be cautious as to where it's grown because it can have a high level of fluoride which is counterproductive to one's health.

Clearly PREVENTION is better than the cure, so as far as it's involvement in treating diabetes there are way better options to consider like DIET FOR YOU MET TYPE, PROPER EXERCISE, EMOTIONAL HEALTH, GOOD QUALITY SLEEP, GOOD FAMILY LIFE and you can top it of with a couple cups of CLEAN organic green tea. I think i'll go pour myself a nice cup now......
 [ Reply ]
  
  
Rita
[ Joined on 11/06 ] [ Posted on September 27, 2007 ]
3 Points        
   
 
Novice User
green tea helps cells become more receptive to insulin so I am not at all surpised by this.  Another reason to keep drinking it, especially matcha which has 8-10 times the antioxidants of regular green tea. 
Rita
 [ Reply ]
  
  
JasonW
[ Joined on 06/06 ] [ Posted on June 28, 2008 ]
       
   
 
Novice User

Green tea is the best I use it every morning it adds a pep in my step. I think every  body should know about it benefits

 [ Reply ]
  
  
debbie lh
[ Joined on 06/06 ] [ Posted on November 4, 2007 ]
       
   
 
Novice User

I find the articles posted on Mercola.com helpful and informative.  The comments posted here are more often a major turn off as so many seem filled with contempt, ridicule of others, sarcasim, hysteria and conspiracy theories.  Most of the comments don't seem helpful or informative.

 [ Reply ]
  
  
jmjatp
[ Joined on 10/07 ] [ Posted on October 16, 2007 ]
       
   
 
Novice User

Dr. Mercola,

I believe that green tea has many beneficial effects on us. What I am concerned about the

caffeine in the green tea. Isn't caffeine is bad for us? There are also decaffeinated green teas, however, the process of making it decaffeinated is not good for our health. What do you think of it?

Thank you for the wonderful e-mails your staff has been sending me. I learned so much from you! Thank you, thank you!

Sonie

 [ Reply ]
  
  
astrolenn
[ Joined on 10/07 ] [ Posted on October 14, 2007 ]
       
   
 
Novice User

For all of you that have put in a comment, your responses have been great. It really makes it worthwhile to follow the comments on the Mercola site. It seems like everything has something that isnt good for you, but like everything you need to take everything in moderation. Me I drink loads of coffee and green tea so I'm getting all the good stuff.

 [ Reply ]
  
  
Pookietooth
[ Joined on 06/06 ] [ Posted on October 13, 2007 ]
       
   
 
Novice User

Green tea makes my teeth feel funny.

 [ Reply ]
  
  
kare4u
[ Joined on 11/06 ] [ Posted on October 13, 2007 ]
       
   
 
Apprentice User

What about white tea? I read it has a higher concentration of antioxidants polyphenols than green tea and because it is the least processed of all teas it does not have the bitterness that green tea has. It is also very low in caffeine. Can anyone confirm this?

 [ Reply ]
  
  
kittycat
[ Joined on 09/07 ] [ Posted on September 25, 2007 ]