Dr. Mercola October 25 2007 109,545 views
Cambridge researcher Aubrey de Grey – featured in this video -- believes aging is a preventable phenomenon, much like a disease, stating that aging is merely a side effect of being alive.
Here he explains his belief that humans could live for centuries, if only we approach the aging process as “an engineering problem.”
He outlines the seven basic ways people age, and how to solve each one. And if we get to work now, he says, humans alive today could live to be 1,000.
According to de Grey, these “7 Deadly Things” are responsible for your physical aging, and are the basis of his “engineering approach” solutions:
Essentially, de Grey’s hypothesis states that if you can keep these seven deadly cell-damaging processes below the threshold of pathology – the state where processes start to break cells down until your body dies from the cumulative damage – you will be able to extend your life indefinitely.
In other anti-aging news, published in Best Life magazine, two preeminent aging experts have placed a bet on whether or not someone living today will be alive in 2150.
Steven Austad, biologist and professor of cellular and structural biology at the Sam and Ann Barshop Institute for Longevity and Aging Studies, believes someone alive today will still be alive in 2150. For the past 20 years, Austad has researched the fundamentals of aging, and has been able to drastically extend the lifespan of various animals by tinkering with their genes, or restricting their calorie intake.
Jay Olshansky, on the other hand, believes there are too many hurdles to be overcome, suspecting any benefit derived from anti-aging drugs will probably be wiped out by rising threats to public health, such as obesity and diabetes. In fact, the demographic models Olshansky and his colleagues have built project that obesity alone will cut the life expectancy of Americans by two to five years within the next 50 years.
Both experts agree, however, that science is making radical advances. Scientists now have a much more detailed understanding of how shutting down certain genes and restricting calories slow your aging process.
The shared factor between all long-lived animals is their superior capability to repair their DNA.
Edward Masoro, at the University of Texas, pioneered research in the 1990’s, showing that a low-calorie diet switches on a key gene called SIRT1 that controls a network of other genes, which in turn create proteins that protect cells from damage. The idea proposed by more than a dozen pharmaceutical companies working on anti-aging drugs, is that you may one day be able to simply take a pill that switches on SIRT1 in your cells.
One such molecule is resveratrol, produced by grapes and other plants. Sirtis Pharmaceuticals, Elixir Pharmaceutical, and about a dozen others are pursuing these kinds of molecular-based anti-aging drugs.
The current old-age record holder is Jeanne Calment, a Frenchwoman who died in 1997 at the age of 122, after smoking for nearly 100 years.
Best Life September 22, 2007(Watch this video: 22 minutes, 55 seconds)
You probably don’t realize it, but Aubrey De Grey is one of the leading anti aging researchers in the world. This lecture he gave at TED is a major treat and will give you insights into what the top thinking in the world is on this subject.
Centenarians, people who live to be 100 years or older, are actually becoming more and more common in the United States. In 1950, there were 2,300 U.S. centenarians and by 2003, there were more than 40,000.
It does not seem unrealistic that in the not too distant future, science will be able to add one year of longevity per year, so the AVERAGE life expectancy could be over 100 years in the next 30 years or so. I believe the current maximum lifespan is about 120 years and any manipulation of genes is unlikely to improve your lifespan significantly beyond that. However the more I study this area, the more I am absolutely convinced that Professor De Grey is absolutely correct, and it is not unrealistic to extend the human lifespan well beyond 120 years old.
Ironically, even though most people express an interest in living to their maximum potential, many people refuse to use the available methods that are sure to slow aging. If they did, we would surely not be facing the ever-increasing epidemics of obesity and diabetes in the United States.
Unfortunately, drug companies are aware of this fact as well and are rapidly jumping on the bandwagon to develop highly unnatural analogs, which they can patent and use to make a handsome profit. You can be virtually guaranteed that these synthetic versions will be grossly inferior to the real deal, especially when it comes to side effects and potential toxicity.
Rather than sitting idly by, waiting for another “magic pill” that will erase old age -- with who-knows-what kind of unforeseen and potentially disastrous side effects -- you can take control of your health, and hence increase your lifespan, NOW.
What Can You do NOW to Maximize Your Lifespan?
If you want to take advantage of the advances in this new science you will need to follow healthy lifestyle principles like the ones I outline below. Probably the most important is normalizing your insulin and leptin levels. There is no way you will age slowly with elevated insulin or leptin levels.
There is no quick fix when it comes to life extension – no pill and no magic fountain. While there are certainly some exceptions -- some centenarians do little in the way of healthy eating or exercise -- for most of us, living a healthy life well into our 100’s will take some dedication to making healthy lifestyle changes, and it's up to you to decide if it’s worth it.
Well put Katie. Your heightened awareness of what is happening as far as polution on various fronts, resulting in the lack of quality of life, will ultimately help you to regain your health. You are reading the right info right here through Dr. Mercola and many other's input of knowledge and useful much needed info. Implementing and finding the individual biochemical balance which will aid recovery is what's challenging...but you will find it. You have a good grasp of contributing factors, which impair optimal health.
God bless you.
Dr. Trudy
How about adding the thought/energy component to the mix here? Do we age/deteriorate partly because we EXPECT to? Doctors tell us that is just a fact of life; we have numerous cliche's about aging and deterioration. If we truly create our own reality, then it it in our best interest to begin believing,acting and speaking as though health, happiness and abudance are given to us as rights by our Creator. Depak Chopra has some amazing writings along this line. Quantum physics seem to be pointing this way! What do we have to lose when we put positive energy forward, believing it is possible? If we all spend our creative time ("work") doing what we love, that energy alone propells us forward in a positve, beneficial light that compounds as it touches others. The book Power vs. Force is another that sheds some amazing light on this subject. The positive/enlightened thoughts of one outweighs the not-there-yet thinking of others. We are reaching a tipping point. Keep up the intent to improvement and better ways!
Hmmm. I must be the opposite of most people.
As a child I had much disease. Over 40 years I learned to stop junk food and eat things as close as I could find to what God created. Then I totally eliminated all disease I used to have. My health is excellent and most people think I will live longer than others.
After an injury a couple years ago (broken head, unconscious seven weeks), I recovered to excellent health when everyone, including doctors expected me dead.
But I have no fear of death, today or tomorrow. Considering the world condition and prospect future, I have no desire to suffer through it. Five years more is quite enough.
I can die any minute, from which I will live forever in a better place.
marvin
My dad is in that better place now.
marvinizinn said, "But I have no fear of death, today or tomorrow. Considering the world condition and prospect future, I have no desire to suffer through it. Five years more is quite enough."
Marvin, you hit the nail "dead on." (Sorry about the pun.) After a life-altering and attitude-altering brush with near-death, I think that your perspective is a realistic, healthy one. I have gone through a different, yet similar, experience as yours. I am content to "go" at any time that my Maker calls me from my Earthly existence. I believe that there is another more satisfying existence in another realm of the Universe. I have no need or desire to "live to 140."
Lynn
I expect I this will be amusing to most people but...........my eye pressure was up to 26 and causing concern to my optician; I regulary have 6 monthly glaucoma checks; although never have had and do not have this.
So..........me being me after reading about how a mental attitude towards health may be beneficial, decided to concentrate my thoughts on the Canal of Schlem; this is the minute vent that allows the eye to release pressure and so maintain a working eye pressure and in turn stops and/or reduces the risk of Retinal damage caused by higher pressures; i.e. glaucoma.
To my surprise and to my opticians surprise........after a few months, my pressure came down considerably.....using my mental model and thought processes targetting the Canal of Schlem.
Whether this mental process worked, I have not idea, but it did.
I have now tried this mental model of my heart; having been diagonised with angina.........targetting a particular restiction.........and something has changed dramatically, it could be the tablets; a combination for medication, diet, exercise, mental thoughts, but there has been a dramatic change from only being able to walk 300 meters in with agonising chest pains to walking 5 miles a day without any problems.
Anyway, it may be my imagination, it may not.......but I certainly feel well indeed.
Dear Freedom,
Aaah, the Power of Positive Thinking, the Power of the Self-Fulfilling Prophecy (you conceive it, you believe it, and the results follow, as expected)... Your reality is what you create all by yourself.
I recommend the film, "What the <<Bleep>> Do We Know" (the extended version). You can rent it, but I purchased the 2-DVD set from Amazon.com. One can watch this unique-style film over and over, and learn something new each time. It's intriguing how some of the concepts of quantum physics relate to (some say "explain") everyday life. You really do create your own reality.
You have discovered the secret to your own healing. Congratulations.
I don't find that "amusing" at all. What you are experiencing is simply a product of human biology. As a whole, we greatly underestimate the power of neurologial impulses either good or bad which has a direct reflection on our fate. If a doctor tells you that you are going to die in 2 weeks and you believe it, it will most likely come true BECAUSE you believed it.
This works with other quality of life factors as well. You simply need to envision your future and how you want it to be and reinforce that vision on a daily basis (see Zig Ziglar) and your subconcious mind will make it happen. Us and our surrouding environment are all made up of energy when you get down to it on a molecular level, and energy can attract and/or repel other types of energy. You may have heard the quote "where you mind goes your energy flows".
If you watch TV and believe the pharmaceutical commercials about everyone having lots of health problems and you are constantly exposed to that and start to believe it, more than likely you will become one of those sick people. Conversely, if you choose your future in your mind and reinforce it, you will become what you imagined. To many this would sound like B.S., and I used to think the same thing, but the more that I use positive mental impulses, the better my life becomes. For example, my business has doubled in the last 6 weeks because of positive imagery and I expect it to double again before christmas.
It sounds so hokey, but choose your future, imagine every detail of everything you want your life to be, even in what order it happens to you. Reinforce that imagery on a regular basis and it will happen to you OVER TIME... you know that the universe didn't sprout from America because it has no want for instant gratification. Just like braces on your teeth... pressure over time yeilds results.