Although several studies have examined the link between cognitive decline and hormone replacement therapy, none has looked at the effect of endogenous estrogen on cognitive function. Differences in endogenous estrogen levels do not appear to be associated with cognitive performance or decline in older postmenopausal women. This new data is in conflict with previous reports that estrogen preserves brain function.

J Am Geriatr Soc 1998;46:816-821,918-920.

Dr. Mercola's Comment:

Another nail in the coffin for postmenopausal estrogen therapy. Last year, NEJM published a study that suggested that estrogen helps prevent Alzheimers disease in women. This information provided another false justification for traditional medicine to prescribe it. If you have not purchased Dr. Lee's book, What Your Doctor May Not Tell You About the Menopause, I would strongly recommend doing so. It is a must reference for all who are interested in natural medicine.