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March 29 2008
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Broccoli Boosts Aging Immune Systems

broccoli, cruciferous vegetableA chemical in broccoli and other cruciferous vegetables may help to restore your immune system as you age. UCLA researchers found that the chemical, sulforaphane, switches on a set of antioxidant genes and enzymes in specific immune cells, which fight the damaging effects of free radicals.

Free radicals are a supercharged form of oxygen that can cause oxidative tissue damage -- for example, they can trigger the inflammation process that causes clogged arteries. Oxidative damage is thought to be one of the major causes of aging.

According to researchers, treating older mice with sulforaphane increased their immune response to the level of younger mice.

The ability of sulforaphane to reinvigorate the immune system abilities of aged tissues could play an important role in reversing much of the negative impact of free radicals.

Dr. MercolaDr. Mercola's Comments:
Cruciferous vegetables like broccoli, cauliflower, kale, turnips and cabbage are full of very powerful disease-fighting compounds, one of which is sulforaphane. This is one compound that appears to be quite a hard worker in keeping your body in top condition.

For instance, sulforaphane has been found to:
  • Boost cell enzymes that protect against molecular damage from cancer-causing chemicals.
  • Increase your liver's ability to detoxify carcinogenic compounds and free radicals. This in turn protects against cell mutations, cancer and other harmful effects.
  • Mobilize, or induce, your body's natural cancer protection resources and help reduce your risk of malignancy.
  • Trigger the production of phase II enzymes, which are among the most potent anti-cancer compounds known.
And now in this most recent study, it appears that sulforaphane also plays a role in preventing oxidative stress. While some level of oxidative stress is a normal result of your body processes, many, many factors, from pollution to obesity to mental stress, can cause an excess of free radicals in your body -- and this is associated with various chronic diseases and aging.

Sulforaphane, however, seems to stimulate a variety of antioxidant defense pathways in your body that can actually fight oxidative stress and slow down the decline in your immune system that happens with age, at least in this study on mice.

In theory, this means that eating vegetables that contain sulforaphane could quite literally slow down the hands of time.

Of course, I know that the burning question on everyone’s mind is …

How Much Broccoli do I Need to Eat?

The amount of nutrients in any vegetable are rarely set in stone. The quality of the soil, how they’re grown (organically or conventionally), how fresh they are, and how they’re cooked all play a role. But, generally speaking, are you wondering how much broccoli you would need to eat to get some of the health benefits mentioned above?

Well, a team of researchers from Johns Hopkins University attempted to calculate how much broccoli you would have to eat in order to produce a significant degree of protection against cancer. They found that you would have to eat an average of about two pounds of broccoli a week in order to reduce, say, your risk of colon cancer by about 50 percent.

However they also ran into problems with this estimate, as depending on the factors I listed above, some broccoli turned out to be “high-inducers” of certain enzymes that provide protective benefits, while others were “low-inducers.” And when the researchers analyzed 22 varieties of fresh broccoli, and seven brands of frozen, their enzyme-inducing abilities varied significantly.

So what’s a health-conscious person to do?

Eat Some Broccoli Sprouts

If you’re looking for the variety of broccoli that will pack the most nutritional punch, broccoli sprouts are as close to a “sure thing” as you will get. Because sprouts are just beginning their growth process, they are packed with high concentrations of vitamins, minerals, amino acids and more. The nutrition in sprouts is so concentrated that they are said to be among the healthiest ways to consume vegetables, and broccoli is no exception.

According to the researchers at Johns Hopkins, just 5 grams (0.17 ounces) of broccoli sprouts contain concentrations of the compound glucoraphanin (a precursor to sulforaphane) equal to that found in 150 grams (5.2 ounces) of mature broccoli.

So you would need to eat 30 times the amount of mature broccoli to get the same nutritional benefits as one serving of broccoli sprouts.

Broccoli is NOT Good for Everyone

As the old saying goes, one person’s trash is another person’s treasure, and this saying can definitely be applied to food. Broccoli may be great for you, or it may push your biochemistry out of balance. How do you know which it is for you? By finding out your nutritional type.

Nutritional typing is based on your genetics, biochemical makeup, family history, and your own interaction with your environment, and it is the only system that customizes nutrition based on the way your body reacts to food.
 
And, as always, listen to your body when it comes to broccoli. Personally, I do not care for broccoli, and that is a giant clue. I am a protein nutritional type, and broccoli pushes my biochemistry in an unhealthy direction.

If you don’t care for broccoli either, no worries. There are plenty of other vegetables and vegetable sprouts out there that offer just as much nutritional punch as broccoli. So find the varieties that you love, and that correspond to your nutritional type, and indulge in those freely.

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Community Comments ( 30 )
Comment on this Article
  
  
wassily
[ Joined on 04/07 ] [ Posted on March 11, 2008 ]
10 Points        
   
 
Savvy User
Don't know if this is fact but - I've read somewhere that the sprouting seeds of broccoli are extemely high in this substance and that one would have to eat massive amount of 'grown' broc to get the same benefits as sprouting broc seeds.  I've founds them really easy to sprout.  I buy a qtr pound bag of certified organic seeds from a health food shop and I get 15 -20 sprouting-jar 'doses' from it - works out approx 10 -13p each time for a jarful of sprouts, here in UK.  Okay, I have to cost in my few minutes labour each day in rinsing them, but as I cannot buy seeds that are already sprouted where I live, then sprouting my own is the only way.  If any of you do try srpouting, experiment with germinating at different moon phases- ie biodynamically - quite interesting! And maybe those of you who can't tolerate grown-up broccoli may be able to tolerate the sprouting seeds?
 [ Reply ]
  
  
mmc88121
[ Joined on 11/06 ] [ Posted on March 10, 2008 ]
10 Points        
   
 
Moderator User
Nel said that the chemistry leading to activation of this gene-regulation pathway could be a platform for drug discovery and vaccine development to boost the decline of immune function in elderly people.
Why don't they just find more ways to get people to eat broccoli, instead of attempting to break it down.  And if you like it better steamed eat it steamed.  I prefer my broccoli raw dipped in homemade hummus.

Mary
 [ Reply ]
Mercola
  
Dekalb
[ Joined on 06/06 ]  [ Posted on March 10, 2008]
12 Points        
   
Savvy User
  Mercola
The broccoli producers need to take a cue from the junk food industry and  market-market-market!
Mercola
  
shaneperrone
[ Joined on 11/07 ]  [ Posted on March 11, 2008]
2 Points        
   
Savvy User
  Mercola
I eat broccoli everyday, i just eat it raw, gets boring once in a while, but i don't really care that bad.
Mercola
  
proatc
[ Joined on 12/06 ]  [ Posted on March 11, 2008]
2 Points        
   
Savvy User
  Mercola
You can make an excellent broccoli soup with just broccoli and sea salt.  Search on you tube for Gordon Ramsay broccoli soup.

Just another way if you are bored. Variety is the spice of life!

Cheers!
Mercola
  
Islander
[ Joined on 03/07 ]  [ Posted on March 29, 2008]
-1 Points        
   
Moderator User
  Mercola

Proatc, dress up the broccoli soup with chicken broth, maybe some cream, lots of butter and a dash of nutmeg. Nom nom nom!

  
  
Donna Scher
[ Joined on 06/06 ] [ Posted on March 28, 2008 ]
7 Points        
   
 
Novice User

Lightly steam broccoli (bite size pieces). Process in a food processor a small amount of feta or goat cheese and your favorite nuts. Add broccoli and some extra virgin olive oil (and sea salt if you like) and chop coarsely in the food processor. Very tasty! Reheats well. Freezes well.

 [ Reply ]
Mercola
  
PatriSpain
[ Joined on 07/07 ]  [ Posted on March 29, 2008]
2 Points        
   
Novice User
  Mercola

@Donna    

Oooooooooo sounds wonderful...thank you for this!!

  
  
ZPE
[ Joined on 02/08 ] [ Posted on March 11, 2008 ]
7 Points        
   
 
Savvy User
Does anyone know if broccoli sprouts have similar levels of sulforaphane?

I hear that the sprouts are fabulous in their own right, so it would be interesting to know if the sulforaphane levels are there as well.
 [ Reply ]
Mercola
  
Faith67
[ Joined on 03/08 ]  [ Posted on March 13, 2008]
4 Points        
   
Novice User
  Mercola
I eat steamed broccoli2-3times a week and I'm fine.  I never try to eat raw.  As far as I know, if it's raw, it's blended...  How anybody here eat raw? 
  
  
Yonatan777
[ Joined on 02/07 ] [ Posted on March 29, 2008 ]
6 Points        
   
 
Novice User

I dont get Mercola's metabolic type stuff..  I read all the articles, but he seems so clear cut as to  what is good and bad.  For example, I feel I am protein metabolic type, because I thrive on cream, cheese, moderate amounts of meat.  I don't feel good a day without sufficient fat and protein.  However, I also like a bit of carbs as I also feel bit cheated, without some small amount of pasta, grains, fruit and veggies.  Now, as far as the veggies I like, the list woudl be this: Spinach, Cauliflower, Broccoli, Zucchini, Tomato, Carrot, Radish, Peas..   The veggies that make me sick , that I hate are: Asparagus, Kale, Chard, Green Beans...   So you , would think from this what am I , protein or mixed?  Well, Mercoal says if I am protein I will hate broccoli but love asparagus, but if I am mixed or carb I will love broccoli and hate aspargus.  But I love cauliflower, spinach and broccoli, but hate the so-called protein veggies, Asparagus, Green Beans (yuck, no mom I wont eat my green beans!)...    Where does this leave me?  Will Broccoli Sprouts (which I love), kill me, becaues I also love spinach???

PLease can a Metabolic type expert help me here.

 [ Reply ]
Mercola
  
drblumers
[ Joined on 03/08 ]  [ Posted on March 29, 2008]
5 Points        
   
Novice User
  Mercola

Hi Yonatan777. Metabolic Type is not written in stone for each person. It is variable for each person to some degree and CAN change with diet alteration, stress, season changes, exercise, and other factors over time. If you are a type O blood type and are hungry for breakfast in the morning, can't skip meals without feeling jittery or foggy, you're probably a protein dominant person and your best choices for meals are good carbs (low glycemic veggies) and proteins with little or no grains, but certainly no refined grains.  How much of what depends on your size and activity level. You CAN also have an aversion to a food that is supposed to "good" for your blood or metabolic type simply because you don't like it for a number of factors (like your mother forced it down you as a kid). Generally speaking, for everyone, avoid all refined carbs, balance good carbs with appropriate proteins according to your blood type, do not consume sodas (diet or otherwise), coffee or black tea, or fruit juices, eat breakfast within one hour or rising in the morning, have three meals a day, drink enough filtered water, and do not eat at least three hours before bed. There you have it in a nutshell (no you can't eat nutshells). There are several good books out there on blood and metabolic type. Good luck.

Mercola
  
Maurine1
[ Joined on 11/06 ]  [ Posted on March 29, 2008]
1 Points        
   
Novice User
  Mercola

I think what Dr. Mercola is saying that if you are a protein type (your body needs and thrives on adequate protein), you must be sure to get enough of it. I know I MUST have meat protein every day or I wither! I too love pastas, etc., but my diabetes cannot handle very much of it. (I've just reached my goal weight at TOPS, and the Zone ratios work best for me.) Recently the healthy-heart lecturer Joe Piscatella spoke in my city and he said red meats are GOOD for your heart, but go for the loin and round (leaner) cuts. I'm putting in another posting on broccoli sprouting, which I've done for years.

  
  
VemmaMel
[ Joined on 06/07 ] [ Posted on March 28, 2008 ]
6 Points        
   
 
Novice User

I appreciate the pointer to eat more broccoli but does it bug anyone that if the minerals aren't in the soils anymore, how can they be in the plant? U.S. Senate document 264 from 1936 documents the fact that American farming practices have depleted the soils of minerals and therefore the only way to get them is to supplement them! www.havewellnessnow.com is a good source for that. ;-)

 [ Reply ]
Mercola
  
Islander
[ Joined on 03/07 ]  [ Posted on March 29, 2008]
8 Points        
   
Moderator User
  Mercola

VedmmaMel, good point. That's one reason why eating organically grown produce is so important. Organic growers use no chemical fertilizers: they build up their soil with compost, including animal manures, so that the nutrition you are expecting - including trace minerals - is in these soils, and thus in the plant. This is not news, it's ancient wisdom, but it's a practice that does not fit the economies of scale of agribiz.

  
  
Charisse
[ Joined on 10/07 ] [ Posted on March 10, 2008 ]
6 Points        
   
 
Apprentice User
I've always heard of the connections between cruciferous veg. and cancer fighters...the question for me is this......is lightly steamed OK?  I can't eat raw broccoli...terrible stomach ache....does cooking interfere?
 [ Reply ]
Mercola
  
Phantom O' Banjo
[ Joined on 09/06 ]  [ Posted on March 10, 2008]
11 Points        
   
Savvy User