Alpha Lipoic Acid: This Antioxidant Dramatically Inhibits Alzheimer's Disease Progression
July 23, 2011
Oxidative stress and neuronal energy depletion are characteristic hallmarks of Alzheimer's disease. It has been hypothesized that, because of this, pro-energetic and antioxidant drugs such as alpha-lipoic acid might delay the onset or slow down the progression of the disease.
In one study, alpha-lipoic acid was given daily to nine patients with Alzheimer's disease. The treatment led to a stabilization of cognitive functions in the study group.
According the study:
"... [T]he progression [of Alzheimer's for patients taking alpha-lipoic acid] appears dramatically lower than data reported for untreated patients or patients on choline-esterase inhibitors in the second year of long-term studies ... [O]ur data suggest that treatment with alpha-lipoic acid might be a successful 'neuroprotective' therapy option."
Separate research also revealed that alpha lipoic acid, in combination with vitamin E and acetyl-l-carnitine, led to improvements in potential biomarkers for Alzheimer's disease and showed promise for slowing the progression of the disease.