Advanced glycation end products (AGEs) are a complex group of compounds formed when sugar reacts with amino acids. This can occur both in the food you eat, and inside your body itself. There is mounting evidence that AGEs may be implicated in the development of the chronic degenerative diseases of aging, including cardiovascular disease, Alzheimer’s disease and diabetes.
Several studies have shown that restriction of the consumption of AGEs can lead to an increased lifespan in animal models.
According to a paper that summarizes recent research on AGEs:
“... [T]he data are supportive that endogenous AGEs are associated with declining organ functioning. It appears that dietary AGEs may also be related ... As of today, restriction of dietary intake of AGEs and exercise has been shown to safely reduce circulating AGEs, with further reduction in oxidative stress and inflammatory markers.”