Vitamin B12 Deficiency Widespread

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August 27, 2000 | 40,659 views

Almost 40% of the U.S. population is deficient invitamin B12 according to a recent study from Tufts University in Bostonand a vast majority of them are completely unaware.

A deficiency of vitamin B12 (cobalamin) deficiencycan cause pernicious anemia, which is marked by fewer but larger red bloodcells. Deficiencies can cause walking and balance disturbances, a lossof vibration sensation, confusion, and even dementia.

Since the body requires B12 to make the protectivecoating surrounding the nerves, inadequate B12 can result in nerve damageas well.

Jean Mayer USDA Human NutritionResearch on Aging at Tufts University, Boston, Mass.


It is important to know that most oral vitamin B12 supplements do not work well at all. Vitamin B12 is the largest known vitamin. It is huge and it is not easily absorbed. Your body has developed a very sophisticated system to absorb B12. This involves the production of intrinsic factor in the stomach which attaches to B12 and allows it to be absorbed in the end of the small intestine.

If your stomach lining is damaged from an ulcer or a Helicobacter infection you will not produce intrinsic factor very well and you will not be able to absorb B12 very well, if at all. An imbalance of bacteria in the small intestine can also produce impaired absorption, as would removal of a portion of the small intestine (commonly done in Crohn's Disease).

Vitamin B12 deficiency is VERY common, almost universal, in strict vegetarians and vegans. Vitamin B12 is NOT readily available, if at all, in plants. It is an animal product. If a vegetarian is eating eggs or fish the risk for B12 deficiency is considerably reduced.

So, if you suspect you are deficient in vitamin B12, I would encourage you to obtain your B12 in a more absorbable form. The common recommendation is to use injections. My recommendation for that would be to use 1 ml once a day for two weeks and then three times a week until the 30 ml bottle is finished. An alternative to the injections would be to use DMSO and vitamin B12. The DMSO causes the B12 to be absorbed very similar to an injection without the cost or pain of a needle. Intranasal B12 is also available, but unless you have a prescription card I would not recommend it, as it is VERY expensive.

One strong inhibitor of vitamin B12 absorption is the very popular drug Prilosec (omeprazole) which has been clearly shown to decrease B12 absorption (Ann Pharmacother 1999 May;33:641-3).

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