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Staying in bed on the weekends won’t make up for a weeks' worth of sleep deprivation. A new study finds that going long periods without sleep can lead to a sort of "sleep debt" that cannot simply be undone with extra sleep later.
Such chronic sleep loss may eventually interfere with a person's performance on tasks that require focus, becoming particularly noticeable at nighttime. This could be due to the effects of your natural sleep-wake cycle, or circadian rhythm.