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New Revelations Support Diet and Exercise to Reverse Leptin Resistance, Thereby Promoting a Healthy Weight

Healthy Diet

Story at-a-glance -

  • Leptin is a powerful and influential hormone produced by your fat cells. It plays a key role in regulating energy intake and energy expenditure. By acquiring a better understanding of how leptin and its receptor interact, researchers now believe they will be able to find new treatments for obesity and other metabolic disorders
  • Drug treatments are not likely to solve leptin resistance, just as they are ineffective and even counterproductive for insulin resistance. The ideal way to correct leptin resistance is through your diet. A strategic whole food diet that emphasizes good fats and avoids blood sugar spikes will enhance insulin and leptin sensitivity
  • According to recent research, being obese promotes the growth of existing tumors regardless of diet, which may help explain why lean cancer patients often have better outcomes than their obese counterparts
  • Previous research has shown exercise can convert cancer-boosting “white” fat cells to the more health-promoting "brown" fat (a heat-generating type of fat that burns energy instead of storing it)

By Dr. Mercola

Leptin, a hormone that plays a key role in regulating energy intake and energy expenditure, may be one of the most important hormones in your body that will determine your health and lifespan. Insulin is another, and the two work in tandem.


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