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More Than 200 Commonly Used Drugs Are Known to Cause Depression as a Side Effect

medication causing depression

Story at-a-glance -

  • Depression can stem from a wide variety of biological, psychological and environmental factors, including other medications. More than 200 drugs have depression as a listed side effect
  • Thirty-eight percent of American adults are on one or more medications that can cause depression as a side effect. Nearly 10 percent are on three drugs or more known to cause depression
  • Seven percent of people who used just one drug associated with depression reported depression. Among those taking two drugs capable of causing depression, the depression rate was 9 percent
  • Those taking three or more drugs known to have depression as a side effect had three times the rate of depression as those who used drugs that did not have depression as a known side effect — 15 percent compared to 5 percent
  • Many drugs also raise your risk of suicidal ideation, and the proportion of adults taking at least one drug where suicide is a potential side effect reached 24 percent as of 2014, up from 17 percent in 2005

By Dr. Mercola

Historically, conventional science views depression as a side effect of a chemical imbalance in the brain. Most pharmaceutical-oriented solutions for depression still to this day revolve around this theory, even though the serotonin-hypothesis has been largely debunked. As noted in a 2014 paper on antidepressants:


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