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What Are the Benefits of Fisetin?

Analysis by Dr. Joseph Mercola

Story at-a-glance -

  • The flavonoid fisetin, which is responsible for the pigment of fruits and vegetables like apples, cucumbers, onions and strawberries, again has been called out for its potential antiaging and neuroprotective properties
  • In experiments involving lab mice, fisetin was shown to eliminate senescent cells — cells that contribute to aging because they have lost their ability to reproduce due to oxidative damage and other cellular stressors
  • Among the health benefits of fisetin, it has been shown to encourage anti-inflammatory action, help prevent cancer and protect your brain function; fisetin can also cross your blood-brain barrier
  • The top food source of fisetin is strawberries, but you’d have to eat at least 37 whole, organic berries at a time to receive a decent amount of the health-boosting properties attributed to this flavonoid
  • Clinical trials are underway at the Mayo Clinic, which may lead to fisetin becoming more widely available and embraced as a dietary supplement

Research on a flavonoid called fisetin, which contributes to the pigment of fruits and vegetables like apples, cucumbers, grapes, onions, persimmons and strawberries, has been called out for its potential antiaging properties. In experiments performed on lab mice, fisetin was shown to eliminate senescent cells, which accumulate as you age and can be harmful to your body.

While fisetin was discovered years ago, it is one of many diet-derived antioxidants being increasingly investigated for its health-promoting effects. As a plant-based flavonoid, fisetin can be consumed for long periods of time without any known adverse effects. Let’s take a closer look at this promising plant pigment.


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