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Spirulina May Be an Effective Treatment for Leptin Resistance

Analysis by Dr. Joseph Mercola Fact Checked

spirulina for leptin resistance

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  • Bilirubin inhibits NOX, a metabolic enzyme that reduces NADPH, which is the most important antioxidant recharging molecule in your body. Phycocyanobilin found in spirulina can inhibit NOX and increase NADPH
  • Elevated bilirubin might aid weight control by preventing the development of leptin resistance, and spirulina may therefore be an effective way to combat leptin resistance
  • Bilirubin also appears to have anti-inflammatory, antioxidant and atheroprotective properties, and spirulina mimics those effects as well
  • Most overweight Americans have some degree of insulin and leptin resistance. This also includes diabetics and many with high blood pressure or high cholesterol
  • If you fall into this category, it would be prudent for you to restrict fructose to about 15 to 25 grams per day from all sources. Spirulina supplementation may also be an effective treatment for leptin resistance

Last year, James DiNicolantonio, co-author of my book, “Superfuel,” published a groundbreaking paper, “Antioxidant Bilirubin Works in Multiple Ways to Reduce Risk for Obesity and Its Health Complications.”

Bilirubin is a breakdown product of red blood cells (heme) and the chemical responsible for the yellow color of bruises, urine and jaundice.


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