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Vitamin C Lowers Mortality in Severe Sepsis

Analysis by Dr. Joseph Mercola Fact Checked

vitamin c thiamine and hydrocortisone for sepsis patients

Story at-a-glance -

  • Sepsis is a last-ditch effort by your immune system to fight an infection in your body; it can lead to multiple organ failure and death unless promptly treated
  • While viruses, fungi and parasites all have the ability to trigger sepsis, bacterial infections are the most common cause. The most common types of infection triggering sepsis are respiratory and urinary tract infections
  • Each year, an estimated 1 million Americans get sepsis and up to half of them die as a result. The reason for its high mortality rate is because sepsis is often overlooked; many are unfamiliar with its signs and symptoms. It’s also notoriously difficult to treat
  • In 2017, a critical care physician announced the discovery of a simple and inexpensive way to treat sepsis using an intravenous cocktail of vitamin C and thiamine in combination with hydrocortisone
  • A 2019 study using vitamin C only found it lowered mortality risk in patients with severe sepsis, and reduced the number of days spent in intensive care and overall hospital stay

One of the leading causes of death in American hospitals is something many are still unfamiliar with: septicemia (sepsis or septic shock). Also known as blood poisoning among lay people, sepsis is a last-ditch effort by your immune system to fight an infection in your body, which can lead to multiple organ failure and death unless promptly treated. As explained by the National Institute of General Medical Sciences:

“The body releases immune chemicals into the blood to combat the infection. Those chemicals trigger widespread inflammation, which leads to blood clots and leaky blood vessels. As a result, blood flow is impaired, and that deprives organs of nutrients and oxygen and leads to organ damage.


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