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Vitamin D Protects Against Infections

Analysis by Dr. Joseph Mercola Fact Checked

vitamin d

Story at-a-glance -

  • Vitamin D upregulates your ability to fight infections, as well as chronic inflammation, and produces over 200 antimicrobial peptides (AMPs), one of which is cathelicidin, a naturally occurring broad-spectrum antibiotic
  • The cathelicidin antimicrobial peptide, or CAMP, is made by immune cells and skin and gut cells, which act as a barrier to infection
  • In general, AMPs are used by your body's innate immune response to kill invading pathogens, including bacteria, viruses, fungi and other pathogens
  • Mice with the human CAMP gene were more resistant to gut infections, and a bioactive form of vitamin D was useful for treating staph infections on the skin
  • Loading vitamin D3 into the nanofibers of a wound dressing significantly increased production of a peptide called hCAP18/LL37, which disrupts the membranes of microbes, effectively killing them

If you don’t know your vitamin D level, getting your blood tested to find out is one of the most important steps you can take to support good health. Low levels of vitamin D are linked to a host of physical and mental problems, while optimal levels protect against chronic disease and infection.

Vitamin D upregulates your ability to fight infections, as well as chronic inflammation, and produces antimicrobial peptides (AMPs), one of which is cathelicidin, a naturally occurring broad-spectrum antibiotic. The cathelicidin antimicrobial peptide, or CAMP, is made by immune cells and skin and gut cells, which act as a barrier to infection.


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