Cholesterol Lowering Drugs May Increase Cancer Risk
September 10, 2000
Spread the Word to
Friends And Family
By Sharing this Article.
Drugs Stimulate Growth of New Blood Vessels By Mimicking Growth Factor
New research indicates that besides lowering levels of harmful cholesterol, the drugs may also promote the growth of new blood vessels, which may not necessarily be such a great thing. Although this effect may help to prevent heart attacks and other forms of heart disease, it may have the potential to promote cancer as well.
Tests in human cell samples and in rabbits, show that the cholesterol-lowering drug simvastatin (Zocor) seems to activate a pathway through which cells communicate and act very similar to a naturally-occurring growth factor, according to Dr. Kenneth Walsh, of Tufts University School of Medicine in Boston, Massachusetts.
Researchers suspect that the drug interacts with a molecule called protein kinase Akt/PKB, which helps regulate blood vessel development properly.
Simvastatin produced similar effects on the growth of new blood vessels, a process called angiogenesis, as does vascular endothelial growth factor (VEGF), a substance essential for healthy blood vessels, according to Dr. Walsh. "The same pathway is being activated by statins as VEGF," he said.
But if statins do promote angiogenesis, the effects may not always be helpful, Dr. Michael Simons, of Beth Israel Deaconess Medical Center in Boston points out in an editorial that accompanies the study.
For example, statins might increase the growth of blood vessels in cancerous tumors, Simons notes. However, even though statins are some of the most widely used prescription drugs, these and other potential harmful effects have not been reported, which calls into question their vessel-promoting abilities, Dr. Simons adds.
Nature Medicine September, 2000;6:965-966, 1004-1010.
Effortless Healing – One Step at a Time – NOW AVAILABLE!
My newest book, Effortless Healing is now available! I've organized this book into a guide that will help you avoid the many pitfalls of the conventional approach to health. Rather than relying on expensive and potentially dangerous drugs, I will help you effortlessly make small shifts in what you eat and how you live to achieve your health goals. I promise, Effortless Healing isn't a book that will overwhelm you. On top of that, ordering the book today entitles you to 3 exclusive bonuses:
A sneak peek of my new book! You won’t need to wait for the book to arrive to get started. Begin reading my new book right away with your free sneak preview!
My most popular video interviews, all in one place. I’ve compiled 18 of my BEST expert interviews for you to watch and listen to at your leisure, and in the comfort of your own home or office.
Receive 15% off your next Mercola.com order. Depending on your order, your savings from this one bonus alone could more than cover the cost of your book!
All My Profits from This Book Will Be Donated
That's right. When you order a copy of my new book Effortless Healing, you'll be making a much-deserved donation to the key organizations that work quietly and efficiently behind the scenes to make the world a healthier place for you, your family, and your community.
Among them, you'll be benefiting and supporting the actions of:
- National Vaccine Information Center (NVIC) – A non-profit organization that seeks to prevent vaccine injuries and deaths through public education and defending your right of informed choice.
- Organic Consumers Association (OCA) – A grassroots public interest organization campaigning for health, justice, and sustainability, and addressing food safety, GMOs, the industrial agricultural complex, children's health, and more. The ONLY U.S. organization focused exclusively on the interests that you and I share!
- Consumers for Dental Choice – Children, the unborn, and employees in the dental field are particularly vulnerable to mercury. But so is everyone with a mouthful of amalgam fillings (which are 50% mercury) at risk. Consumers for Dental Choice is working to phase out amalgam use and to promote access to mercury-free alternatives.
- Fluoride Action Network (FAN) – An international coalition aimed at ending water fluoridation and alerting you to fluoride's environmental and health risks. FAN keeps you informed about fluoride toxicity, and monitors government actions that may expose you to fluoride.
Are you ready to get started? The timing has never been better. Order your copy of Effortless Healing today, collect your free gifts, and let your journey begin!