These drugs, known collectively as NSAIDs, are believed to reduce or inhibit substances critical to maintaining and regulating pressures in the lungs and can cause persistent pulmonary hypertension of the newborn (PPHN).
Babies who suffer from PPHN are more likely to have a range of problems after birth and often must be placed on a respirator to help them breathe.
Several previous studies have also shown a link between NSAIDs taken during pregnancy and the development of PPHN in newborns.
Researchers in this study conclude that pregnant women should be made better aware of the dangers associated with taking over-the-counter drugs containing NSAIDs.
Pediatrics Vol. 107 No. 3 March 2001, pp. 519-523
It would be best to avoid ALL medications when pregnant. Regardless of what anyone tells you, there is no drug that is 100% proven safe during pregnancy. However, in the case of a condition that is life-threatening or severely disabling, the benefit would be worth the risk, in most cases. Clearly this is not the case with NSAIDs, which are taken for symptomatic relief only.