By Mohammed Ali Al-Bayati, Ph.D., DABT, DABVT
Introduction
Review of the literature of the causes and the pathogenesis of AIDS worldwide revealed that approximately 90% of AIDS cases in the USA and Europe are observed in homosexual men and drug users.
The regular uses of alcohol, heroin, cocaine, amphetamines, and alkyl nitrite cause chronic health problems of the nervous system, respiratory system, cardiovascular system, kidneys and other tissues in these individuals.
The majority of these health problems are usually diagnosed as idiopathic currently, and treated with high doses of glucocorticoids and/or cytotoxic drugs. In addition, as a group, homosexual men are heavier users of illicit drugs, alcohol, and rectal glucocorticoids than their heterosexual counterparts.
The HIV-hypothesis states that HIV causes AIDS by killing the CD4+ T cells directly or indirectly after long incubation times (about 10 years), and the number of these cells will reach very low levels (<300/ µL) which lead to severe immune deficiency.
Patients with severe immune deficiency (CD4+ T cells < 200/µL) usually suffer from opportunistic infections (viral, bacterial, fungal, yeast, and/or parasitic) and certain forms of cancer such Kaposi's sarcoma (KS) and lymphoma.
It follows that treatment of patients with antiviral drugs, such as inhibitors of reverse transcriptase (AZT) or protease, is believed to delay the progression of AIDS by preventing HIV replication in the cells.
However, the treatment of a patient with prednisone at 60 mg per day for about three months can actually cause AIDS. This treatment and doses often given to patients suffering from lung fibrosis, thrombocytopenia, or other chemically induced chronic illnesses.
The majority of AIDS patients who participated in the four major Zidovudine (AZT) clinical trials in the US between 1987-1992 were HIV-negative prior to their treatment with AZT. Briefly, a total of 2,349 patients participated in these studies, and at least 77% of them were HIV-negative prior to their treatment with AZT.
The reversal of damage in the immune system in HIV-positive patients following the cessation of the insulting agents and the reporting of large number of HIV-negative AIDS patients, combined with the wide use of immunosuppressive agents in modern medicinal practice, motivated me to review the medical literature to evaluate the validity of the HIV-hypothesis and the contribution of the illicit drugs, alcohol, therapeutic agents, and malnutrition to the pathogenesis of AIDS worldwide.
Duesberg stated that HIV is harmless virus and AIDS in homosexual men and drug users in the industrial countries is caused by the heavy use of illicit drugs. He also stated that AIDS in hemophiliacs is caused by foreign-protein contaminating commercial clotting factor VIII and not by the HIV.
The correct approach for investigating AIDS causes or pathogenesis of any other complicated chronic medical problem is by evaluating all medical evidence concerning each risk group. Namely, a differential diagnosis that considers both infectious and noninfectious causes of diseased should be performed.
I used differential diagnosis in this case and it indicated that HIV is not the cause of AIDS. It also indicated that the use of illicit drugs alone or the use of antihemophilic factors does not cause AIDS.
AIDS is caused by the heavy use of corticosteroids and/or cytotoxic drugs to treat many health problems resulted from the use of illicit drugs by drug users and homosexuals.
The appearance of AIDS cases in the USA in 1978 coincided with approval of corticosteroids aerosol by the US FDA in 1976. In addition, homosexual men are usually heavy user of rectal glucocorticoids.
AIDS in hemophiliacs is caused by the use of corticosteroids and other immunosuppressive drugs to prevent the formation of antibodies for factors VIII and IX and to treat other health problems.
Causes and Pathogenesis of AIDS In Drug Users and Homosexuals
In the USA, the total cases of AIDS in adults was 573,800 as of January 1, 1997 and about 90% of these cases were male homosexuals and heterosexuals and homosexual drug users.
The appearance of AIDS in the USA and Europe in drug users and homosexuals in the late 1970's and early 1980's coincided with the synergistic actions of several events.
Briefly, these include the spread of illicit drug use, especially smoking crack cocaine and heroin in 1970's, the approval of glucocorticoids aerosol by the US FDA in 1976, the wide use of the glucocorticoid inhalers to treat chronic respiratory illnesses resulting from inhaling cocaine and heroin, the wide use of alkyl nitrites by homosexuals to facilitate anal sex in 1970's, and the wide use of corticosteroids to treat chronic gastrointestinal tract illness in homosexuals.
Furthermore, the approval of antiviral drugs (AZT and protease inhibitors) and the steroids by the U.S. FDA to treat patients with AIDS and asymptomatic patients infected with HIV has exacerbated the problem.
In addition to illicit drug and alcohol abuse, homosexuals are also heavy users of alkyl nitrites that relax the anal muscle and facilitate anal sex. It has been stated that the use of alkyl nitrites permeated the gay life by 1977.
Homosexuals usually suffer from acute and chronic rectal and gastrointestinal diseases that dictate the heavy therapeutic use of rectal steroids. Among 7 selected studies that included 736 patients (97% of them were homosexual or bisexual men) who were infected with HIV and/or had AIDS.
They show clearly that homosexual men suffer from extensive rectal and gastrointestinal problems that result in chronic use of therapeutic rectal steroids.
Review of the medical literature revealed that the short and the long term use of glucocorticoids at therapeutic doses, resulted in a variety of effects on the immune system that range from a transient reduction in T cells count in peripheral blood to the development of full blown AIDS.
Fauci described in detail the effects of corticosteroids on the immune system. These effects resemble the immune abnormalities that are found in patients suffering from AIDS or Idiopathic CD4 T cells lymphocytopnea (ICL) which are also described by Fauci et al.
Since the defect with corticosteroids is broad, it is not surprising that many types of infections seem to occur more often in patients treated with corticosteroids. Of the bacterial infections, staphylococcal and Gram-negative infections, as well as tuberculosis and Listeria infections, probably occur most often.
Certain types of viral, fungal, and parasitic infections also occur often. Patients with lupus erythematous, rheumatoid arthritis, and renal transplant have more infection with steroid administration. Studies of bronchial aerosols showed that with higher doses of steroid in the aerosol, Candida infections of the larynx and pharynx occurred more often".
Causes and Pathogenesis of AIDS In Infants and Children In USA and Europe
The prevalence of drug and alcohol abuse during pregnancy is very high both in the USA and Europe. The results of nine large studies surveying the prevalence of drug use in relation to the outcome of pregnancy in the USA showed that up to 15% of pregnant women used cocaine during pregnancy based on a positive urine test.
The impact of illicit drug and alcohol abuse during pregnancy on infant health is very serious as shown in nine studies that included 1,295 drug using mothers and 4,293 nonusers.
The use of cocaine during pregnancy was usually associated with a high prevalence of premature births and low birth weights. Drug exposed infants usually had immature lung profiles and other serious health problems that were treated with glucocorticoids.
Fauci also explained the serious impact of illicit drugs on the pregnant mothers and her infants. They stated that "women who abuse cocaine have reported major derangement in menstrual cycle function, including galactorrhea, amenorrhea, and infertility.
Chronic cocaine abuse may cause persistent hyperprolactinemia as a consequence of cocaine-induced disorders of dopaminergic regulation of prolactin secretion by the pituitary. Cocaine abuse, particularly the smoking of crack by pregnant women, has been implicated as causing an increased risk of congenital malformations and of prenatal cardiovascular diseases in the infants.
Cocaine abuse per se is probably not the sole reason for these prenatal disorders since many problems associated with maternal cocaine abuse, including poor nutrition and health care status as well as polydrug abuse, also contribute to the risk of prenatal diseases".
The treatment of the mother expected to have a premature birth with glucocorticoids has been used as a standard procedure since 1970s. Glucocorticoids are used to facilitate the development of the lung and to reduce the incidence of necrotizing enterocolitis in premature infant. In addition, the natural cortisol levels in plasma and urine of the cocaine-exposed preterm neonates is significantly higher than in normal infants.
Discussion
The proponents of the HIV-hypothesis must be aware of the impact of illicit drug and alcohol abuse on health. However, they choose to discount the AIDS connection. Fauci stated, "a markedly higher age-specific mortality rate among injection drug users in the general population was documented even before the epidemic of infection with HIV and AIDS.
For example, in New York City between 1965 and 1972, the death rate among relatively young (20 to 54-year-olds) adult heroin addicts not involved in drug-treatment programs was estimated to be five times greater than that among age-matched non-heroin-addicted adults.
The list of health problems induced by drug and alcohol abuse and those resulting from practicing receptive anal sex that required treatment with steroid is extensive. The chronic use of high doses of steroid (40-60 mg per day for several months) can cause AIDS as described in this report.
As also stated above, the chronic use of rectal steroid reduced the CD4+ T cells in HIV positive homosexuals. Suppose that a homosexual man has a 1000 CD4+ T cells/µL prior to using rectal steroids to treat the wide range of chronic health problems.
Alpha lipoic acid is a powerful antioxidant that has been used to prevent injury caused by chemicals in vivo and in vitro and injuries in diabetic patients for the last two decades. It has been used in Europe to reverse peripheral neuropathy in diabetic patients and has been shown to be effective and safe in several clinical trials.
This drug is very effective in preventing and reversing injuries resulting from metabolic changes and/or exposure to chemicals that induce lipid peroxidation. This medication should be given to people with AIDS to help boost the immune system and to heal tissue injury.
The medical evidence describing the effect of malnutrition on lymphoid tissues is extensive (Fauci et al., 1998). Fauci et al. (1998) also described the health problems in hemophilia patients, such as the formation of inhibitors for factors VIII and XI, the joint problems, and the use of immunosuppressive agent in the treatment regimen of these patients.
Yet, they seem to ignore all these facts and claim that the problems in these patients is caused by HIV which leads to the treatment of these very sick people with extremely toxic drugs (AZT and protease inhibitors).
AIDS patients have been treated with antiviral medications based on the assumption that the HIV causes AIDS.
However, decreasing the plasma viral load does not restore the immune system. The thymus and the lymphoid tissues have very high rates of regeneration. A 50% destruction of the thymus by a chemical agent was restored within 10 days after cessation of exposure. If the cause of AIDS is HIV and the antiviral drugs are reducing the viral load, then the patients would recover within days.
Furthermore, according to the clinical trial results of the major four studies on the AZT conducted in the USA between 1987-1992, at least 77% of the patients were HIV-negative prior to their treatment with AZT.
However, it has been claimed that AZT prolonged lives. The antiviral medications and the glucocorticoids not only fail to cure AIDS but they cause severe damage to sick people. The proponents of the HIV hypothesis failed to anticipate this disaster.
The logical steps that should be taken to prevent AIDS and to cure people with AIDS are:
This is a yet to be published paper by Dr. Al-Bayati of Toxi-Health International.
Mohammed Ali Al-Bayati, PH.D, DABT, DABVT Toxi-Health International 150 Bloom Dr. Dixon, CA 95620 Phone: (707) 678-4484
ABOUT THE AUTHOR
Dr. Al-Bayati received his Ph.D. from the University of California Davis in Comparative Pathology and is a board certified toxicologist (American Board of Toxicology and American Board of Veterinary Toxicology). With over 20 years of experience in research, teaching, diagnostic work and consulting, Dr. Al-Bayati has extensive expertise in evaluating data from observational and experimental studies in humans and animals and applying this knowledge effectively to real-life situations.
Dr. Al-Bayati firmly believes that a correct appraisal of information from animal and human exposure events is essential to arrive at a proper understanding of the nature and extent of the injury and in the search for the correct treatment. Consequently, he has also served as an expert witness in cases related to exposure of humans and animals to toxic agents.
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For many, this will be new information, although Dr. Duesberg and Dr. Horowitz have been taking similar positions for many years.
Dr. Al-Bayati provides a solid piece of scientific support for the position that HIV does not cause AIDS. Exposure to steroids and the chemicals in our environment, the drugs used to treat AIDS, stress and poor nutrition are possibly the real causes.
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