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Pregnant women who use non-steroidal anti-inflammatory drugs
(NSAIDs) and aspirin increase their risk of miscarriage by
80 percent. The risk was increased if the NSAID use took place
around the time of conception or if the drugs were used for
more than one week.
Researchers suggest that the drugs suppress the production
of prostaglandins, which are fatty acids needed for successful
implantation of an embryo into the womb. The drugs may therefore
lead to abnormal implantation that increases the chance the
embryo will miscarry.
British
Medical Journal August 16, 2003
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