Frustration may not be the only consequence of failing to ditch those excess pounds in midlife, for middle-aged obesity could increase one's risk of dementia--the decline of cognitive functioning--later on, according to a study.
Researchers reviewed the medical records of more than 10,000 people (between ages 40-45) who were members of the Kaiser Permanente health plan in Northern California from 1964-73. They conducted a follow-up on the health of the participants some 20 years later.
By 1994, physicians found 7 percent of the patients surveyed had been diagnosed with dementia. The results proved to be linked to body mass index (BMI), a ratio of weight to height:
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People with a BMI of 30 or above were 74 percent more likely to succumb to dementia than those of healthy weights.
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Those in the 25-29.9 BMI range had a 35 percent greater chance of dementia.
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Obese, middle-aged women were more prone to dementia, though both men and women who were the fattest were 60 percent to 70 percent more likely to have dementia than those who had the lowest levels of fat.
To make sure they had a pure link between obesity and dementia, researchers took into account other factors such as cardiovascular health and diabetes; they didn't examine, however, the physical activity of those surveyed, making it uncertain whether lack of exercise could play a part in the development of dementia.
So Why Does Obesity Lead to Dementia?
Though there is only speculation, one theory is that high-fat diets may damage the brain. Researchers also explained that obesity could lead to inflammation, causing problems in the brain.
British Medical Journal April 29, 2005 (Free Full-Text Article)
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