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March 29 2008
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Diesel Fumes Damage Your Brain

diesel, exhaust, fumes, brain damage, beta, air pollutionInhaled diesel exhaust triggers a stress response in the brain. This could have damaging long-term effects on brain function in people living in areas with high traffic pollution.

Small particles of soot, or nanoparticles, can travel up the nose and lodge in the brain. It is conceivable that this could interfere with normal brain function and information processing.

10 male volunteers, aged 18 to 39, were placed in a room filled with exhaust from a diesel engine for one hour. After about 30 minutes, EEG brain wave patterns displayed a stress response, suggesting changes in information processing in the brain cortex.



Dr. Mercola Dr. Mercola's Comments:

As it turns out, breathing polluted air over the long term not only increases your risk of dying from lung cancer or heart and lung disease, it may also increase your risk of neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease, according to this new study.

What are You Breathing?

Air pollution is produced by combustion, such as burning of gas by automobile engines and fuel burning at power plants. It consists of tiny solid and liquid particles that can be inhaled deep into your lungs as you go about your day.

Most particles are microscopic, but you can still see the haze that forms when millions of them blur the spread of sunlight.

These pollutants can cause inflammation in your lungs or prompt your body to release chemicals that can affect heart function. Although science has not been able to pin-point the exact pathway explaining how or why air pollution is so toxic to you, statistics show that as levels of fine particulates and sulfur oxide-related pollution in the environment rises, so does the death rate from lung cancer and cardiopulmonary diseases, which include heart attack, stroke, asthma, pneumonia and chronic obstructive pulmonary diseases like emphysema and bronchitis.

The differences in the sizes of the particles that make up air pollution make a big difference in how they affect you.  

Your natural defenses will help you cough or sneeze larger particles out of your body. But those defenses can’t defend you from smaller particles (smaller than 10 microns in diameter, or about one-seventh the diameter of a strand of human hair).  

Those particles get trapped in your lungs, while the smallest are so microscopic they can actually pass through your lungs into your bloodstream, just like the essential oxygen molecules you need to survive.  

Health Dangers of Pollution 

More than 2,000 peer-reviewed studies have been published on air pollution since 1996, when the EPA last reviewed the standards for particle pollution. These studies prove that there is a very strong relationship between pollution, illness, hospitalization and premature death from any cause

Researchers are now investigating whether there are any differences in health effects of the three sizes of particles and particles from different sources, such as diesel particles from trucks or sulfates from coal-fired power plants. This study, for example, looks at how diesel fumes might affect your brain function, and the results are less than encouraging. 

So far, the evidence remains clear that ALL particles from ALL sources pose significant health hazards.  

And, you don’t even need long-term exposure to increase your risk of disease and premature death. According to the latest findings, as reported in the 2007 American Lung Association State of the Air report, SHORT-TERM exposure to pollution has been linked to:

  • death from respiratory and cardiovascular causes, including strokes
  • increased mortality in infants and young children
  • increased numbers of heart attacks, especially among the elderly and in people with heart conditions
  • inflammation of lung tissue in young, healthy adults

  • increased hospitalization for cardiovascular disease, including strokes and congestive heart failure
  • increased emergency room visits for patients suffering from acute respiratory ailments
  • increased hospitalization for asthma among children
  • increased severity of asthma attacks in children

What Happens When You Pollute Your Brain? 

This study, which was published in the journal Particle and Fibre Toxicology, found that the molecular toxicity of diesel exhaust creates oxidative stress-mediated inflammation in your brain cortex. (Inflammation is already considered to be the central causative factor in both pulmonary and systemic diseases from exposure to diesel fumes.) 

Your brain is extremely sensitive to damage caused by oxidative stress.  

For example, oxidative stress is implicated in the development of neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease.  

This kind of stress in the brain cortex is also found in other psycho-pathological ailments such as: 

  • headaches
  • post-traumatic stress disorder
  • “burnout”
  • traumatic brain injury 

The researchers found that the beta waves in the test subjects in this study were significantly affected, whereas the alpha, theta, and delta waves were not altered to any great degree.  

So what does that mean? 

Well, your brainwaves range from the most activity to the least activity. Beta waves are generated when your brain is aroused and actively engaged in mental activities. These waves are the fastest of the four brainwaves (21-32 Hz).  

If you’re in active conversation with someone, you’re in beta. A debater, public speaker or teacher is in high beta. Anytime you’re actively engaged in your work, you’re in beta. It’s certainly not a brain function you’d want to have impaired. 

This picture shows how the left side of the frontal cortex is lit up on the test subjects who were exposed to diesel fumes, compared to the control group. 

They suggest this effect might be due to either:  

  1. nanoparticles that slowly penetrate the brain itself, or
  2. nanoparticles that affect neurophysiologic signaling through some other pathway 

Either way, air pollution is a serious concern that spells trouble for both your body and your brain, regardless of how it works. 

How Toxic is Your City? 

The latest State of the Air report for 2007 also lists the Best and Worst cities for air pollution in the United States. Los Angeles-Long Beach-Riverside, CA takes the prize for Most Polluted Year-Round, and, I’m sad to say, my hometown of Chicago, IL ranks number 11 out of the top 25.  

The only silver lining, for me personally, is that Honolulu, HI came in as the third cleanest-air city in the U.S., which is where I spend part of each year.

Final Thoughts

As you become more and more informed about the toxic dangers that surround you and the natural, non-toxic alternatives that do exist, you will find that it’s not enough to pay attention to one thing only, because it’s all interconnected and changes need to be made in many areas to optimize health (both on a personal and world-wide level).

If you aim for Total Health, reviewing your diet; water supply; your healthcare; personal care products; cleaning products; the fabrics and materials used in your home and interior design; your clothing; and the quality of the air you breathe, just to rattle off a few of the concerns – ALL of it becomes important as all of it DOES impact your quality of health.

But there are safer alternatives for everything these days! And I will continue sharing them with you, so that together we can be the change we want to see.

Also remember that my site contains more than 150,000 pages of health information, so don’t forget to SEARCH for the information you need. More than likely, the answer is right at your fingertips!


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Community Comments ( 41 )
Comment on this Article
  
  
curlilox
[ Joined on 08/07 ] [ Posted on March 12, 2008 ]
15 Points        
   
 
Savvy User
I think anyone placed in a room filled with diesel exhaust for an hour would have major problems! 
Good grief!  Let's gas you for an hour and see how you feel!!
 [ Reply ]
Mercola
  
ZPE
[ Joined on 02/08 ]  [ Posted on March 12, 2008]
9 Points        
   
Savvy User
  Mercola
Ha! Wonder if the researcher got them to sign a disclaimer saying that they wouldn't sue him if they got brain damage later on in life?

Probably the 'volunteers' were unknowing first year students at the university!
Mercola
  
jeffa
[ Joined on 02/08 ]  [ Posted on March 12, 2008]
6 Points        
   
Novice User
  Mercola
So that is what iterns are for! :P
Mercola
  
HilaryB
[ Joined on 12/07 ]  [ Posted on March 29, 2008]
1 Points        
   
Novice User
  Mercola

I remember taking intro psychology in college - part of your grade was based on completing 6 experiments ... so basically you went and were a guinea pig for the professor's area of study. The only one I went to was a written exam type thing but I decided after that that I wasn't going to go to the rest so I don't know if they would have gone as far as experimenting on us (I never really asked anyone else what they went to.) It did make me angry though that paying to go to college, part of my grade was based on being a free test subject.

I do know someone else who recruited people at bars for a test that involved motor skills I think and it was based on half the group getting non-alcoholic beer and the other half getting real beer. Neither group knew which they were getting (so it led to drunk acting non-drunks) so that again makes me wonder what the participants of this study were told... "Oh yeah, we're going to see you're brain's reaction to smoke as if you were in a burning house. Here's $200 sign this waver." Sometimes people react based on what they are told. Also if there were visible fumes, wouldn't you start to stress and worry after awhile?

Yeah, I'm still pretty sure exposure to diesel fumes aren't good though - I'm not debating that.

Mercola
  
Gazer
[ Joined on 03/08 ]  [ Posted on April 1, 2008]
       
   
Novice User
  Mercola

Who in their right mind volunteers for these studies? You couldn't pay me to do some of these unhealthy research studies. They're probably desparate college kids.

  
  
EQ
[ Joined on 03/07 ] [ Posted on March 12, 2008 ]
8 Points        
   
 
Savvy User
Let's not throw the baby out with the bathwater here.  I'm sure being in a room with ANY exhaust would do damage.  The newer clean burning diesel engines are more efficient, less polluting, and get better gas mileage than regular gas engines.  My parents' small diesel car does better than a Prius overall.

You can also modify the diesel to run on veggie oil (recycled is probably the most sustainable).  It looks like the most promising & immediately available alternative fuel these days might just be diesel made from algae.  The plant oils such as corn, hemp, switchgrass, etc. aren't nearly as efficient/sustainable.  National Geographic just ran a big article on this.

I would be thrilled if completely non-polluting electric & perhaps hydrogen engines were developed, but in the meantime, we need something else soon.
 [ Reply ]
Mercola
  
pisces
[ Joined on 06/06 ]  [ Posted on March 29, 2008]
4 Points        
   
Novice User
  Mercola

There is the issue of the finer nanosized particles of gasoline emissions burrowing even deeper into lung tissue than the diesel exhaust counterparts, which are about ten times larger.

See the following link for an in-depth analysis of the effects of gasoline exhaust:

toxsci.oxfordjournals.org/.../485

... and remember, the idiots in our legislature refuse to roll speed limits back to 55mph. Lower speeds would allow smaller engines to realistically operate on our freeways. That's when our country could take advantage of the 70 -90 mpg diesels available in Europe.

  
  
davidh19471
[ Joined on 08/06 ] [ Posted on March 29, 2008 ]
6 Points        
   
 
Novice User

Well, the things I've noted concerning long-term diesel exposure are:

The necessity of listening to country music 24/7

Development of a distinct southern drawl

Desire to be on the road at all times

Strange habits, such as addressing all women as "hon," "darlin," "you shore are a purdy lil thang," and the like

Opening conversations with strangers in diners with "Whatchya haulin?"

Believing in God

Believing in America

Serving both with pride and honor :)

 [ Reply ]
Mercola
  
LoriSmi
[ Joined on 01/08 ]  [ Posted on March 29, 2008]
1 Points        
   
Novice User
  Mercola

Well David,

These must be the good side-effects that diesel causes! Isn't anything wrong with what you said~except maybe the C&W music! :)

Mercola
  
Shadeaux
[ Joined on 01/08 ]  [ Posted on March 29, 2008]
4 Points        
   
Novice User
  Mercola

 You forgot voting Republican, and still being a proud Bush supporter(and people wonder who those 19% are)

Mercola
  
ozseppo
[ Joined on 06/07 ]  [ Posted on March 30, 2008]
-4 Points        
   
Novice User
  Mercola

not to mention blaming, the "gummit", for everything

Mercola
  
EQ
[ Joined on 03/07 ]  [ Posted on April 4, 2008]
       
   
Savvy User
  Mercola

Oh there are 2 distinct paths the side effects can take.  One is your way, the other is the way of the biodiesel/veggie oil converting tye-dye wearing hippy.  Oh well, I guess I'll just have to get some organic biodegradable dye & tie up some t-shirts.  I won't start listening to the Grateful Dead, however.  I respect them immensely, their music just doesn't do it for me.

  
  
mmc88121
[ Joined on 11/06 ] [ Posted on March 11, 2008 ]
6 Points        
   
 
Moderator User
I have always wondered why anything that smells that bad could be good for you.  Now we are finding out it is not.  But did the room also have an outside air source?  Or was it just the diesel fumes that were pumped into it?  That can make a big difference.

Mary
 [ Reply ]
Mercola
  
Aaltrude
[ Joined on 04/07 ]  [ Posted on March 11, 2008]
4 Points        
   
Savvy User
  Mercola
I used to work in a room where the air conditioning system brought in outside air - from a polluted city street and would have contained diesel fumes among other things. I now have Multiple Chemical Sensitivity.
  
  
flbooks7
[ Joined on 01/08 ] [ Posted on March 12, 2008 ]
5 Points        
   
 
Apprentice User
This is very interesting to me because my father developed alzheimers disease when he was in his mid 60's.  I couldn't figure out why because he did just about everything right.  He ate garden vegetables, wild moose, and wild Alaskan salmon.  He was outdoors breathing clean Alaskan almost always when he was home.  He was rarely in the house.  He kept a good weight all his life and was very strong.  So strong that we had a hard time finding a long term care situation that could handle him when he his disease progressed beyond what we could take care of at home.  The only think that I could think of that could have hurt him was that he was a mechanic for the Army and worked on diesel buses.  The cold air kept the fumes down near the floor when the shop doors were open and sometimes the door couldn't be kept open because of the extreme cold.  The fumes and the fact that he had his hands in parts cleaner so much...that's all I could think of that could have caused it.
 [ Reply ]
Mercola
  
Beccadog
[ Joined on 10/07 ]  [ Posted on March 30, 2008]