How Does Aspartame Damage Your Brain?

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Dr. Mercola
April 26 2008

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How Does Aspartame Damage Your Brain?

Consuming a lot of aspartame may inhibit the ability of enzymes in your brain to function normally, according to a new review by scientists from the University of Pretoria and the University of Limpopo.

The review found that high doses of the sweetener may lead to neurodegeneration. It has also previously been found that aspartame consumption can cause neurological and behavioral disturbances in sensitive individuals.

Specifically, the review found a number of direct and indirect changes that occur in your brain as a result of high consumption levels of aspartame, including disturbing:

The metabolism of amino acids
Protein structure and metabolism
The integrity of nucleic acids
Neuronal function
Endocrine balances

Further, the breakdown of aspartame causes nerves to fire excessively, which can indirectly lead to a high rate of neuron depolarisation.

Despite these growing concerns, neither the European Food Safety Authority (EFSA) or the U.S. Food and Drug Administration (FDA) have changed their guidelines regarding the safety of the ingredient or intake advice.

Sources:

Food Quality News April 6, 2008

European Journal of Clinical Nutrition 2008, 62, 451–462

Dr. Mercola's Comments:

Aspartame is a poison that does not belong in your body, and this is not an exaggeration. Yet, this toxic substance is consumed by over 200 million people around the world and is found in more than 6,000 products.

Everything from soda and chewing gum to desserts, yogurt, and even some vitamins and cough drops contain it.

When you drink, say, a can of diet soda sweetened with aspartame, what are you REALLY consuming? Here’s a breakdown of aspartame’s three chemicals: the amino acids aspartic acid and phenylalanine, and methanol.

1. Aspartic acid (40 percent of aspartame)

Aspartate acts as a neurotransmitter in your brain by facilitating the transmission of information from neuron to neuron. Too much aspartate in your brain kills certain neurons by allowing the influx of too much calcium into your cells. This influx triggers excessive amounts of free radicals, which kill your cells.

The neural cell damage that can be caused by excessive aspartate is why Dr. Russell Blaylock refers to them as "excitotoxins." They "excite" or stimulate your neural cells to death.

Now, when aspartic acid is consumed, it significantly raises your blood level of aspartate, which leads to a high level of those neurotransmitters in certain areas of your brain, where they slowly begin to destroy neurons.

Your brain cells could be dying right now, but you likely would not notice the symptoms until 75 percent or more are gone. Then, chronic illnesses such as the following, which may by caused by long-term exposure to excitatory amino acid damage, may occur:

Multiple sclerosis, Parkinson’s disease and Alzheimer’s disease
Memory and hearing loss
Hormonal problems
Epilepsy
AIDS
Brain lesions
Neuroendocrine disorders

2. Phenylalanine (50 percent of aspartame)

Phenylalanine is an amino acid normally found in your brain, however people with the genetic disorder phenylketonuria (PKU) cannot metabolize phenylalanine. This leads to dangerously high -- and sometimes lethal -- levels of phenylalanine in your brain. It has been shown, though, that ingesting aspartame, especially along with carbohydrates, can lead to excess levels of phenylalanine in your brain even if you do not have PKU.

Even consuming aspartame one time has been found to raise your blood levels of phenylalanine. What’s the risk of this?

Excessive levels of phenylalanine in your brain can cause the levels of serotonin in your brain to decrease, leading to emotional disorders such as depression. It can also cause schizophrenia or make you more susceptible to seizures.

3. Methanol (aka wood alcohol) (10 percent of aspartame)

Methanol/wood alcohol is a deadly poison, and the absorption of methanol into your body is sped up considerably when free methanol is ingested. Well, free methanol is created from aspartame when it is heated to above 86 degrees Fahrenheit (30 Centigrade). This would occur when an aspartame-containing product is improperly stored (in the sun, for instance) or when it is heated, such as part of a "food" product like Jello.

Meanwhile, methanol breaks down into formic acid and formaldehyde -- a deadly neurotoxin -- in your body.

Even the U.S. Environmental Protection Agency (EPA) states that methanol "is considered a cumulative poison due to the low rate of excretion once it is absorbed. In the body, methanol is oxidized to formaldehyde and formic acid; both of these metabolites are toxic."

They recommend a limit of consumption of 7.8 mg/day, but a one-liter aspartame-sweetened beverage contains about 56 mg of methanol. Heavy users of aspartame-containing products consume as much as 250 mg of methanol daily -- or 32 times the EPA limit!

The symptoms of methanol poisoning are numerous and varied. They include:

Vision problems
Headaches, ear buzzing, dizziness
Nausea and gastrointestinal disturbances
Weakness, numbness and shooting pains in your extremities
Behavioral disturbances
Memory lapses

Do You STILL Believe Aspartame is Safe?

I could literally go on for days about the many problems plaguing this artificial sweetener; both the dangers it poses to your health and the blatant greed and manipulation that got it on the market.

That is why I spent years researching and writing Sweet Deception. It is the most comprehensive book on the market addressing this issue, and if you or your loved ones drink diet beverages or eat diet foods, please read it sooner rather than later.

I also highly recommend watching Sweet Misery, which is part documentary, part detective story that sheds much-needed light on the controversy surrounding aspartame.

Folks, aspartame is not your friend. It is actually responsible for 80-85 percent of the food complaints registered with the FDA!

Aside from the damage it can do to your brain, aspartame can cause cancer. One well-controlled, peer-reviewed, SEVEN-year study even found that as little as 20 mg per day can cause cancer in humans.

One 12-ounce diet soda contains about 180 mg of aspartame, so you do the math on that risk!

If you have NutraSweet or Equal packets in your home, I urge you to get rid of them. About the only good use for them I’ve heard about is using them to kill ants in your kitchen.

And if you’re consuming diet foods or drinks of any kind, toss those as well. Your health will be much better off for it.

If you find you’re still having sweet cravings or are having a hard time giving up your diet soda, Turbo Tapping is a simple tool to help you get rid of your soda addiction in a short period of time. And in the case of aspartame, getting it out of your diet can’t come fast enough.

Related Links:

One Woman's Astonishing Experiment With Aspartame

NutraSweet Shown to Cause Cancer

Aspartame Disease: An FDA-Approved Epidemic

Community Comments (62)

Posted On Apr 07, 2008

This is not new information. It has been described by Russell Blaylock in his book "Excitotoxins, The Taste that Kills" which was published in 1997.

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Aaltrude

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HealthCoachSandraG

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Posted On Apr 08, 2008

YES!!!

Blaylock's book points to the dangers of Aspartame from Parkensons and Alzheimers to learning disabilities and Autism. He also highlights the dangers of MSG. I've always wondered if Splenda was rushed to the market because Aspartames days were numbered. Now we'll have to wait years of being human guinea pigs to see what that (splenda/sucralose) fake food does to humans.

MSG needs the same negative press. It's just has harmful.

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Islander

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Posted On Apr 26, 2008

FTR, Blaylock does cover MSG as well as aspartame in his book.

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4 Points

Posted On Apr 08, 2008

"Neither the European Food Safety Authority (EFSA) or the U.S. Food and
Drug Administration (FDA) have changed their guidelines regarding the
safety of the ingredient or intake advice."

Preaching to the choir, I know, but if those findings were against a vitamin, herbal remedy, or raw milk - the FDA would have closed them down before you could say 'habeas corpus'.

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23 Points

ZPE

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Posted On Apr 08, 2008

And yet, millions of people continue to eat this poison. So many people are so uneducated about these artificial sweeteners. It's so sad how the public is constantly being duped. I bought a box of stevia into the office today. My co-workers' husband has diabetes. She had no clue about stevia and how its derived from a plant and there is no chemicals in the product. She read the box - she even made a xerox copy of the box for her mom. People just don't think about educating themselves about the foods they eat.

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Linda24

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Posted On Apr 26, 2008

Life is simple. If man made it don't eat it. READ LABELS.

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sally t

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Voltaire

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Posted On Apr 26, 2008

Yes! We really do need to adhere to this simple rule for a Healthy Life.

I am very pissed that an exiting FDA commissioner approved Aspartame as G.R.A.S

(Generally Recognized as Safe) This single action by a corrupt man has resulted in Aspartame being hidden in thousands of prepared foods like cake mix, etc.

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6 Points

Posted On Apr 07, 2008

This needs to be forwarded to every one you know who uses aspartame as a warning, because it will not be in the news.

Mary

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mmc88121

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VMC

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Posted On Apr 08, 2008

I was affected by aspartame in 1997 and have been waiting "patiently" for the FDA to recind it's approval. It's not happening and I'm tired of trying to aviod foods with aspartame and telling my kids that they can't chew the gum in conventional grocery stores. I'm ready to speak out for myself and others who have been affected by this poison. If you know of anyone in Florida, who has been affected by aspartame, please direct them to my blog: www.mptampabay.blogspot.com

I'm trying to get a support group together in my area in order to produce awareness and, hopefully, invoke some type of change. Thanks.

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VMC

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Posted On Apr 08, 2008

Just one of the affects,,, sometimes I don't spell things right. :)

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