How Light Helps Fight Psoriasis
May 23 2009
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Ultraviolet light is a proven treatment for psoriasis, and sunshine itself can also beat back the chronic autoimmune disorder of the skin. But explaining light’s therapeutic effects has been difficult.
A new clinical trial is attempting to find out the reasons. Researchers have recruited the first of what will be 20 patients who will visit the hospital three times a week for up to four months to receive narrowband ultraviolet light B (UVB) treatment. Patients will give skin and blood samples as the treatment takes its course, giving the scientists the possibility to study what is happening at the molecular level as the skin gets better.
UVB therapy is known to kill off T cells, which are partly to blame for the inflammation caused by the disease. UVB may target a pathway involving two immune system proteins called cytokines, which could disrupt certain types of T cells and another specialized group of immune-directing dendritic cells.
| Vitamin D Dose Recommendations |
| Below 5 | 35 units per pound per day |
| Age 5 - 10 | 2500 units |
| Age 18 - 30 | 5000 units |
| Pregnant Women | 5000 units |
WARNING: There is no way to know if the above recommendations are correct. The ONLY way to know is to test your blood. You might need 4-5 times the amount recommended above. Ideally your blood level of 25 OH D should be 60ng/ml. |