In 2003, research showed that resveratrol, a powerful polyphenol and anti-fungal chemical, was able to increase the lifespan of yeast cells. The results ignited flames of hope for an anti-aging pill. According to the findings, resveratrol could activate a gene called sirtuin1, which is also activated during calorie restriction in various species.
Since then studies in nematode worms, fruit flies, fish, and mice have linked resveratrol to longer lives. Other studies with only resveratrol have reported anti-cancer effects, anti-inflammatory effects, cardiovascular benefits, anti-diabetes potential, energy endurance enhancement, and protection against Alzheimer’s.
Resveratrol is found in grapes and red wine, and has particularly been associated with the so-called 'French Paradox' -- the low incidence of heart disease and obesity among the French, despite their relatively high-calorie diet and levels of wine consumption.