The effect of cranberry proanthocyanidins (PACs) is dependent on the dose. Higher doses are significantly more effective at maintaining urinary health.
A new study supports the theory that at least 36 milligrams of proanthocyanidins (PAC) are needed to reduce the adhesion of E. coli bacteria to urinary tract walls. A lower dose proved to be less effective.
However, according to NutraIngredients:
“On the other hand, a higher dose of 72 mg was even more efficient at protecting against bacterial adhesion in the urinary tract, according to findings published in the open-access journal BMC Infectious Diseases.”