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If You Can't Beat Depression, Your Gut Bacteria Could be the Reason


This is an older article that may not reflect Dr. Mercola’s current view on this topic. Use our search engine to find Dr. Mercola’s latest position on any health topic.

Researchers examined the performance of germ-free mice, who lack gut bacteria, on a kind of maze used to test anxiety-like behaviors. The maze is in the shape of a plus with two open and two closed arms; normally, mice will avoid open spaces to minimize the risk of being seen by predators.

Normal mice, as expected, spent far more time in the closed arms when placed in the maze. The germ-free mice, however, entered the open arms far more often, spending significantly more time there than in the closed arms.


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