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Orlistat: This Popular Weight Loss Drug May Cause Permanent Liver and Kidney Damage


Story at-a-glance

  • Weight-loss drug orlistat (Xenical and Alli), even at low levels, inhibits a major detoxification enzyme (carboxylesterase-2) in the liver, kidney and gastrointestinal track, which may lead to “severe toxicity of internal organs such as the liver and kidney”


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