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Oral Pathogens

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  • Two independent new studies found a causal link between a common oral bacterium (F. nucleatum) and colorectal cancer; pathogens in your mouth can enter your bloodstream to colonize other parts of your body
  • The same pathogenic bacteria has been known to cause stillbirths in mice, but was recently found responsible for a pregnant woman’s intrauterine infection that resulted in her baby’s tragic stillbirth
  • Chronic, untreated human papillomavirus (HPV) infection is associated with more than just cervical cancer; an estimated 60 to 80 percent of all oropharyngeal cancers stem from HPV infections of the mouth
  • The bottom line is that oral hygiene is even MORE important than previously thought, to reduce pathogenic microbes that can travel from your mouth to other parts of your body and cause disease
  • Consuming naturally fermented foods and incorporating “oil pulling” with coconut oil are two effective ways of balancing your oral and gut flora, which will improve your oral health, as well as your overall health
 

Pathogens in Your Mouth Can Lead to Cancer in Other Parts of Your Body

March 05, 2014 | 313,771 views
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By Dr. Mercola

Good oral hygiene is even more important than previously thought. Pathogenic microorganisms and their toxins can harm more than just your mouth when they circulate through your bloodstream—they can potentially cause secondary infections and chronic inflammation throughout your body.

The fact that oral pathogens can make their way to distant parts of your anatomy and cause serious problems has been known for many years.

Even dentists would agree that bacteria can pass from your gums into your bloodstream and on to your heart, which is why some still prescribe oral antibiotics to a few select patients with a particularly high risk for endocarditis, particularly if they have gingivitis.1

But it appears that the rare case of endocarditis is only the tip of the iceberg. Several studies now show that these oral pathogens—viruses as well as bacteria—may be linked to certain cancers, making it even more important to do take every step possible to ensure your teeth and gums stay healthy.

Poor Oral Health Is a Risk Factor for Oropharyngeal Cancers

The human papillomavirus (HPV),2 some strains of which are associated with cervical cancer if left untreated for long periods of time, has similarly been linked to vaginal, vulvar, penile, anal, and oropharyngeal cancers (cancers of the throat, tonsils, and base of tongue).

Hence the ridiculous recommendation to vaccinate boys with the notorious HPV vaccine, Gardasil, which is riddled with dangerous side effects and other problems. A new study published in the journal Cancer Prevention Research reports:3

"Poor oral health, which includes dental problems and gum disease, is an independent risk factor for oral HPV infection, and by extension, could also contribute to oral cancers."

In this study, participants with poor oral health had a 56 percent higher rate of HPV infection than those with healthy mouths. Centers for Disease Control and Prevention states that about 60 percent of oropharyngeal cancers are related to HPV,4 but according to the latest study, it could be as high as 80 percent.

The researchers speculate that good oral hygiene could help prevent HPV infection, thereby lowing your risk for oropharyngeal and other cancers. Human papillomavirus is actually a group of more than 100 viruses. Of those 100, about 40 are sexually transmitted, and 15 of those are the types most often associated with cervical cancers and genital warts.5

It is important to note that more than 90 percent of women infected with HPV clear the infection naturally within two years, at which point their cervical cells return to normal. It is only when the HPV virus lingers for many years (that is, becomes chronic) that abnormal cervical cells could turn into cancer.

This is why regularly scheduled PAP smears prevent cervical cancer deaths far more effectively than the HPV vaccine ever will, because they allow a sufficient amount of time to find and treat any cervical abnormalities.

Viruses Cause 15 to 20 Percent of All Cancers

It is interesting to note that HPV isn't the only virus linked to cancer—in fact, it is estimated that 15 to 20 percent of all cancers are caused by viruses!6 Many viruses trigger cancer by suppressing your immune system and/or altering your genes. The following viruses are known to play a major role in certain types of cancer:7

  • EBV (Epstein-Barr virus) increases your risk for nasopharyngeal cancer, certain lymphomas and stomach cancer
  • Hepatitis B and C are linked to liver cancer
  • HIV is associated with invasive cervical cancer, lymphoma, lung cancer, liver cancer, anal cancer, oropharyngeal cancer, skin cancer and Kaposi's sarcoma; Herpes virus 8 is also thought to be involved with almost all cases of Kaposi's sarcoma

Three New Studies Prove Oral Bacteria Can Cause Colorectal Cancer

There is one bacterium that has been causing a great deal of trouble with people's health: Fusobacterium nucleatum, a spindle-shaped anaerobic bacterium commonly found in dental plaque. F. nucleatum is abundant in your mouth and able to coaggregate with other species.8 Three recent studies have linked F. nucleatum with serious health problems:

  1. Case Western Reserve University researchers found that some malignant colorectal tumors are caused by F. nucleatum9
  2. Harvard researchers also established a link between F. nucleatum and the initiation of colorectal tumors10
  3. A study in Journal of Obstetrics and Gynecology found that oral F. nucleatum can lead to intrauterine infection and even stillbirth11

The first two studies establish an actual causal link between this bacteria and colorectal cancer. The bacteria trigger inflammation and also activate the cancer growth genes and the signals required for angiogenesis to occur (a tumor's blood supply). Normally, F. nucleatum is not prevalent in your gut, but if your microbial balance is off—which can happen in your mouth, as well as in your gut—then it's able to invade and colonize. F. nucleatum has been found in gut mucosal biopsies that show inflammation and in biopsies of colorectal tumors.12

The third study discusses an unusual case of a mother losing her baby to stillbirth due to an intrauterine infection, directly resulting from gingivitis. The bacteria moved from her mouth to her uterus because her immune system was weakened by a respiratory infection. Other studies have shown these bacteria to cause stillbirths in mice, but this was the first documented human case.13

All of these studies unequivocally show that bacterial imbalances and dysbiosis can contribute to inflammation in your body and activate cancer genes. Therefore, the bacteria in your mouth deserve as much care and attention as the ones in your gut. Not surprisingly, they're interrelated, and as you improve your gut flora, the flora in your mouth improves accordingly. I experienced this myself. When I started consuming fermented vegetables, it only took a few months before I was able to reduce the frequency of my visits to my dental hygienist for a persistent plaque problem.

Another Danger: A Mouthful of Mercury

Besides oral hygiene, which I'll be discussing shortly, there are two other dental-related concerns you may need to address: mercury amalgams and fluoride. The average American has eight mercury amalgams (fillings), falsely described as "silver" fillings. This misleading label has been purposely used to keep you in the dark about the exact composition of the fillings, which are actually about 50 percent mercury. Mercury is a toxic heavy metal that can poison your brain, central nervous system and kidneys. Children and fetuses, whose brains are still developing, are most at risk—but anyone can be adversely impacted.

Mercury is such a potent toxin that just one drop in a lake would poison the lake to the extent that the Environmental Protection Agency (EPA) would ban fishing in it. Yet, they claim that carrying around a mouthful of mercury fillings has no harmful effects. If you have mercury amalgams, it would be advisable to consult a holistic, mercury-free dentist.

Steer Clear of Fluoride in Any Form

If you are using fluoridated toothpaste, you may want to consider tossing it out and replacing it it with a safe one. In the mornings, you could use toothpaste containing calcium and phosphate salts, or even hydroxyapatite, which can help remineralize your teeth. Baking soda will help promote beneficial bacteria in your mouth by neutralizing the acid that pathogenic bacteria thrive in. I use an oral irrigator with baking soda twice a day and follow with coconut oil pulling for 20 minutes.

Fluoride is of little or no benefit to your teeth and poses serious health risks, including immune dysfunction, endocrine disruption, increased risk of fractures, arthritis, infertility, and many more.

Toothpaste isn't the only source of fluoride—it is present in growing numbers of non-organic foods from pesticide residue (including iceberg lettuce). And fluoride continues to be added to many municipal water supplies in the United States. Water fluoridation has come under increasing scrutiny as health concerns, lack of efficacy in preventing tooth decay and ethical issues of administering chemicals via the water supply have surfaced. For more information on fluoride, please watch the presentation by Michael Connett, an attorney with the Fluoride Action Network in this previous article.

Four Strategies for Improving Your Oral Health

The latest research uncovering the connection between the microorganisms in your mouth and cancer make it extraordinarily clear that oral hygiene is a necessary prerequisite if you want to be healthy. Major problems can result from the overgrowth of opportunistic oral pathogens, including oropharyngeal cancers, colorectal cancer, and if you're an expectant mother, even the tragedy of stillbirth. In addition to avoiding fluoride and mercury fillings, my top four recommendations for optimizing your oral health are as follows:

  1. Consume a traditional diet: fresh fruits and vegetables, grass-pastured meats, poultry, eggs, and dairy; nuts and seeds; minimal consumption of sugar and processed food
  2. Add in some naturally fermented foods, such as sauerkraut, pickles, kimchee, yogurt, kefir
  3. Proper brushing and flossing
  4. Oil pulling

A traditional diet will help balance both your oral and gastrointestinal flora, but it may not be enough to guarantee perfect oral health. I've struggled with plaque for years, and it wasn't until I added fermented foods and oil pulling that I began to make progress with the problem. The addition of fermented foods decreased my plaque by 50 percent and made it much softer, and the oil pulling has improved it further.

Oil Pulling Is Like Giving Your Teeth an 'Oil Change'

Oil pulling is an ancient Ayurvedic practice dating back thousands of years. When it harnesses the antimicrobial power of coconut oil, you have one very powerful tool! The high lauric content of coconut oil makes it a strong inhibitor of a wide range of pathogenic organisms, from viruses to bacteria to protozoa. Researchers in Ireland found that coconut oil treated with enzymes, in a process similar to digestion, strongly inhibits Streptococcus bacteria, which are common oral residents that can lead to plaque buildup, cavities, and gum disease.

Oil pulling can lessen your toxic load by pulling out pathogens and preventing their spread to other areas of your body. When done correctly, oil pulling has a significant cleansing, detoxifying and healing effect. Oil pullers have reported rapid relief from systemic health problems such as arthritis, diabetes and heart disease. Sesame oil is traditionally recommended, but it has a relatively high concentration of omega-6 oils. Therefore, I believe coconut oil is far superior, and to me it tastes better. But from a mechanical and biophysical perspective, both oils likely work.

Oil pulling is simple. Basically, it involves rinsing your mouth with about a tablespoon of coconut oil, much like you would using a mouthwash. The oil is "worked" around your mouth by pushing, pulling, and drawing it through your teeth for a period of about 15 minutes. If you are obsessive like me, you can go for 30-45 minutes. This process allows the oil to neutralize and "pull out" bacteria, viruses, fungi and other debris. After working the oil around for 15 minutes, spit it out and rinse your mouth with water. Do NOT swallow the oil as it's loaded with bacteria and toxins. Naturopathic physician and coconut oil expert Bruce Fife compares the benefits of oil pulling to changing the oil in your car:14

"It acts much like the oil you put in your car engine. The oil picks up dirt and grime. When you drain the oil, it pulls out the dirt and grime with it, leaving the engine relatively clean. Consequently, the engine runs smoother and lasts longer. Likewise, when we expel harmful substances from our bodies our health is improved and we run smoother and last longer."

Your Diet Is Key to Reducing Chronic Inflammation

The running thread linking a wide variety of common health problems, including cancer, is chronic inflammation in your body – regardless of whether it originates in your mouth or not. Clearly, addressing your oral health is an important step, but it really all starts with your diet.  

Your diet can make or break your teeth, as it were, and has a profound effect on your overall level of inflammation. Therefore, to optimize your health and prevent many of the diseases listed above, you'll want to evaluate your lifestyle to ensure you're doing everything you can to prevent chronic inflammation from occurring. To reduce or prevent inflammation in your body, you'll want to avoid the following dietary culprits:

  • Sugar/fructose and grains
  • Oxidized cholesterol (cholesterol that has gone rancid, such as that from overcooked, scrambled eggs)
  • Foods cooked at high temperatures
  • Trans fats

Beyond that, brushing with baking soda and using oil pulling can help address the bacterial balance in your mouth. The most important factor, however, is to regularly reseed your gut with beneficial bacteria, i.e. probiotics. Fermented vegetables and other traditionally fermented foods are an ideal source, but if you don't eat fermented foods, then a high-quality probiotic is certainly recommended.

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