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CBD Has Unique Ability to Cross Blood-Brain Barrier

Analysis by Dr. Joseph Mercola Fact Checked

cbd ability to cross blood brain barrier

Story at-a-glance -

  • Your body has a barrier to keep foreign chemicals from accessing your brain and spinal cord. Researchers have discovered by coating nanocapsules with CBD oil, they could carry particles into the brain of mice
  • CBD is the nonpsychoactive component of cannabis, which has strong anti-anxiety effects. Its ability to cross the blood-brain barrier suggests your brain has cannabinoid receptors used to maintain health
  • Although it’s normal to be concerned, too much stress and anxiety steals your time, energy and health; according to the World Health Organization, by 2030 global costs of anxiety treatment are expected to reach $147 billion annually
  • Low levels of endocannabinoids impact your risk of migraines, fibroids, irritable bowel syndrome and neurological conditions, but using CBD alone is not the answer to support your endocannabinoid system (ECS)
  • Natural ways to boost your ECS include avoiding pesticides, optimizing omega-3 intake, fasting, exercise and reducing stress

The cannabis plant has over 400 chemicals and at least 60 different cannabinoids — chemical compounds the human body is uniquely equipped to respond to. Of the two primary chemicals, cannabidiol (CBD) and tetrahydrocannabinol (THC), only THC has psychoactive properties.

THC is the compound in cannabis triggering a "high," whereas CBD has no psychoactive effects. Both compounds, and other phytochemicals found in medical marijuana plants, have a long list of beneficial effects on health.


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