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December 18 2004
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Women Convert Crucial Fat for Fetuses Better Than Men

 

It's known that women need the good fat docosahexaenoic acid (DHA) during pregnancy, as it's crucial in the development of the fetal brain. If women do not consume seafood, in which DHA is naturally found, they must synthesize DHA from fatty acid precursors in vegetable foods such as flax seeds.

Researchers set out to determine whether DHA acts differently in men and women, and whether the sex hormones were involved, and found that women are able to convert fatty acids to DHA more readily than men.

In the study, researchers compared men and women who ate the same diets. It was found that women had more DHA than men, and women taking oral contraceptives had more DHA than women not taking oral contraceptives. Individuals who received the oral hormone estradiol had the largest increases in DHA, whereas DHA decreased in subjects who took testosterone.

Researchers concluded that estrogens cause higher DHA concentrations in women than in men, likely because of the need to protect the fetus in pregnant women. It is thought that the higher DHA concentrations occur because women are able to synthesize more DHA from vegetable sources than men.

American Journal of Clinical Nutrition November 2004 80(5);1167-1174



Dr. Mercola Dr. Mercola's Comments:

Omega-3 fats are considered essential fats because our body cannot make them, and therefore must take them in through our diets. For the most part the most valuable omega-3 fats are the longer chain fats like DHA and EPA that are nearly exclusively found in fish oils. Humans have a very limited capacity to convert smaller and less useful omega-3 fats like the ALA found in flax oil, to the more useful higher order fats EPA and DHA.

Earlier studies were really clear in showing that fish oils work far better than flax oil for controlling inflammation, which is one of the corner stones of all chronic disease. That is why C-Reactive Protein levels, which measure inflammation in the body, are so important in monitoring disease.

The longer fat DHA is absolutely critical for developing healthy infants. Well, it turns out that women do indeed have a better ability to produce DHA from the ALA in flax than men do. This appears to be related to the hormone estradiol, so this capability is only present in menstruating women and is likely related to a protective benefit for producing healthy children.

After saying all this I want you to understand that the difference was not large -- on average it was equal to about 60 mg of DHA, which is the DHA present in about one-half capsule of most fish oils.

So what is the bottom line here?

While I am absolutely delighted that infinite wisdom has provided a backup to protect developing fetuses, I remain ever insistent that the ideal form of omega-3 supplementation is indeed fish or cod liver oil. It makes no sense not to take the real deal when working with something so precious as optimizing health and life function. Yes, one can consume flax, but it is best consumed as freshly ground organic flax seeds and should never be used as the primary source of omega-3 fat.

Those of you looking for my favorite source of omega-3 fat, Carlson's fish oil and cod liver oil, can find it in our Recommended Products section or in your local health food store.

Related Articles:

Flaxseed Oil Does Not Increase Essential DHA in Breast Milk

Fish Oil Reduces Heart Disease: The Evidence Increases

Cardiovascular Benefits of Omega-3 Fats

Flax Seed Oil Actually Increases Prostate Cancer While Fish Oil Decreases It

Pregnant Women May Not Be Getting Enough Omega-3

Fish & Cod Liver Oil--Not Flax--Lower Inflammation

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